Additional file 2 of mTORC1-mediated acquisition of reward-related representations by hippocampal somatostatin interneurons
Bibliographic record
Abstract
Additional file 2: Figure S2. Deceleration correlation over training, and speed, acceleration, and deceleration correlations with mean learning index; and basal Ca2+ activity in SOM-Rptor-KO mice. A Mean correlation of Ca2+ activity with deceleration for all SOM-INs decreased at the end relative to the start of training in control but not in SOM-Rptor-KO mice. B Mean speed correlation as a function of mean learning index for all animals, showing correlation in control but not SOM-Rptor-KO mice. C Mean acceleration correlation as a function of mean learning index for all animals, showing absence of correlation. D Mean deceleration correlation as a function of mean learning index for all animals, showing correlation in control but not SOM-Rptor-KO mice. E Mean speed correlation as a function of mean place correlation for all animals, showing correlation in control but not SOM-Rptor-KO mice. F Examples of simultaneous measurements of position and Ca2+ responses during a training session from 7 SOM-INs of a control mouse and from 5 SOM-INs of a SOM-Rptor-KO mouse. G Ca2+ responses of a representative SOM-IN from a SOM-Rptor-KO mouse at start and end of training. Top: mean Ca2+ responsesand speed as function of position for all trials with reward zone indicated in green. Bottom: color-coded Ca2+ activity in each trial of the session, showing activity uncorrelated with position at the start and end of training. H Correlation of Ca2+ responses with position across laps at sessions 3 and 16, showing no place correlation at start and end of training. For each left: place correlation matrix of all paired laps. For each right: distribution of r values, mean r versus r distribution obtained by shuffling position measures. I-K Mean ΔF/F, mean standard deviation of ΔF/F and mean speed correlation in failed trials of the first 3 sessions of training, showing no difference between basal Ca2+ activity of SOM-INs of control and SOM-Rptor-KO mice during behavior-matched periods. L Mean spatial information content of SOM-IN activity during the last 3 sessions of training showing no difference between SOM-INs of control and SOM-Rptor-KO mice. Details of statistical tests provided in Additional file 5: Table S1. * p < 0.05, ** p < 0.01, *** p < 0.001, ns not significant.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.017 |
| Meta-epidemiology (narrow) | 0.002 | 0.001 |
| Meta-epidemiology (broad) | 0.002 | 0.001 |
| Bibliometrics | 0.002 | 0.003 |
| Science and technology studies | 0.001 | 0.000 |
| Scholarly communication | 0.002 | 0.002 |
| Open science | 0.003 | 0.001 |
| Research integrity | 0.002 | 0.001 |
| Insufficient payload (model declined to judge) | 0.893 | 0.214 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".