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Potential Moderators For Outcome After Rotator Cuff Repair : a Pilot Study

2017· other· en· W6946095664 on OpenAlexaboutno aff

Bibliographic record

VenueBiblioBoard Library Catalog (Open Research Library) · 2017
Typeother
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicGenomics and Phylogenetic Studies
Canadian institutionsnot available
Fundersnot available
KeywordsRotator cuffPsychosocialLogistic regressionOutcome (game theory)Quality of life (healthcare)Minimal clinically important differenceStepwise regressionClinical trialPatient-reported outcomeShoulder surgeryScale (ratio)

Abstract

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Background and aimThere is a growing body of evidence, that central pain processing (CPP) and psychosocial factors may maintain or drive shoulder pain. In patients undergoing rotator cuff repair (RCR,) findings report that patientsu2019 expectations may predict outcome after surgery 1. Yet, there is a lack of evidence on modifiable factors that potentially moderate the outcome after RCR. The aim refers to identify such moderators for outcome after RCR. MethodsThe longitudinal study will investigate 141 datasets of adult patients undergoing RCR at Kantonsspital Winterthur, Switzerland. Mean change of three measurement points, 1. pre-operative, 2. 12 weeks post-operative, 3. 12 months post-operative of primary (Western Ontario Rotator Cuff Index (WORC)) and secondary outcome measures (Constant u2013 Score, maximum pain and quality of life) will be analysed by mixed-effects regression model for repeated measures. Stepwise inclusion of the 6 potential moderators will be conducted using linear and logistic regression models. Potential moderators are obtained by quantitative sensory testing and central sensitisation inventory (CPP), pain catastrophizing scale, illness perception questionnaire, perceived stress scale and questions about expectations and sleep.ResultsAssessments started in September 2018. Preliminary results from the pilot study will be available in summer 2019 and may provide insight in short-term prognosis for outcome 12 weeks postoperative. ConclusionResults may disclose moderators for outcome after RCR and foster a more patient-centred treatment approach with the aim to tailor the course of care towards a beneficial outcome. Funding acknowledgementAcknowledgments refer to the staff of Kantonsspital Winterthur. Ethical approval ID: 2018-02089.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Scholarly communication, Insufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Other · Consensus signal: Other
Teacher disagreement score0.118
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0030.001
Science and technology studies0.0010.000
Scholarly communication0.0020.000
Open science0.0040.007
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.067
GPT teacher head0.347
Teacher spread0.280 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designNot applicable
Domainnot available
GenreOther

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2017
Admission routes1
Has abstractyes

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