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Record W6949838861 · doi:10.5281/zenodo.15528175

Hemostasis and Fibrinolytic Enzyme Secretory Microorganisms

2025· book· en· W6949838861 on OpenAlexaboutno aff

Bibliographic record

VenueZenodo (CERN European Organization for Nuclear Research) · 2025
Typebook
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicEnzyme Production and Characterization
Canadian institutionsnot available
Fundersnot available
KeywordsPlasminFibrinFibrinolysisFibrinogenHemostasisPlateletFibrinolysin

Abstract

fetched live from OpenAlex

Copyright © 2025 A9.com LLC or its affiliates. Published Heritage Branch, Library and Archives Canada. All rights reserved. No part of this publication may be reproduced, distributed, or transmitted in any form or by any means, including photocopying, recording, or other electronic or mechanical methods, without the prior written permission of the publisher, except in the case of brief quotations used in critical reviews or scholarly articles.This book is a work of academic and scientific research. While every effort has been made to ensure the accuracy and reliability of the information presented herein, the authors and publisher accept no responsibility for any errors or omissions or for any consequences arising from the use of this material.Fibrin is the main protein component of a blood clot. Fibril is formed fibrinogen by the action of thrombin. Fibrin strands trap platelets, red blood cells, and plasma, forming a clot. When a clot forms, a large amount of plasminogen is release into the blood stream. Plasminogen does not convert to plasmin until it is activated, and it will not dissolve the blood clot.in this case, plasminogen is activated by Tissue-type plasminogen activator, which, after activation, is converted to a substance called plasmin (or fibrinolysin). But because of pathophysiological disorders, the fibrin hydrolysis is not complete due to a balance disorder, thrombosis, such as a myocardial infarction and cardiovascular diseases, can occur. but fibrinolytic drugs available are expensive and they have side effects such as short half-life, create allergic, atherosclerosis and etc. fibrinolytic enzyme hydrolyzes fibrin and cause open the blood vessels. Fibrin enzymes have been discovered from both food and non-food sources. Among them, microorganisms are used as the preferred reference for the production of new fibrinolysin enzymes with variable properties due to their rapid growth, limited medium requirement for cultivation, and ease of genetic manipulation of DNA. The microorganism under studies, have a good ability to produce the enzyme fibrinolysin.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Other · Consensus signal: none
Teacher disagreement score0.013
Threshold uncertainty score0.044

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.001
Scholarly communication0.0020.001
Open science0.0000.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0130.008

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.016
GPT teacher head0.222
Teacher spread0.206 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreOther

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2025
Admission routes1
Has abstractyes

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