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Record W6950355364 · doi:10.5281/zenodo.4439344

Analysis of helicobacter pylori eradication on platelet counts of adult patients with idiopathic thrombocytopenic purpura

2020· article· en· W6950355364 on OpenAlexaff

Bibliographic record

VenueZenodo (CERN European Organization for Nuclear Research) · 2020
Typearticle
Languageen
FieldMedicine
TopicHelicobacter pylori-related gastroenterology studies
Canadian institutionsContinental (Canada)
Fundersnot available
KeywordsHelicobacter pyloriThrombocytopenic purpuraEsophagogastroduodenoscopyPlateletSerologySpirillaceaeAntibodyDuodenum

Abstract

fetched live from OpenAlex

Introduction: Helicobacter pylori(H. pylori) is a gram-negative microaerophilic bacterium that colonizes the stomachs of over half the human population.Objectives of the study: The main objective of the study was to analyse the helicobacter pylori eradication on platelet counts of adult patients with idiopathic thrombocytopenic purpura.Material and methods: This descriptive study was conducted in University College of Medicine & Dentistry, University of Lahore during March 2019 to November 2019. The study included all adult patients of both sexes, who were diagnosed with ITP. If platelet count and patient status allowed, we diagnosed H.pylori infection was by histological examination of different biopsies obtained from different areas of stomach and duodenum (including the gastric antrum) via esophagogastroduodenoscopy (EGD). IF EGD is not applicable, we diagnosedH. pyloriinfection by the positivity of serum antibodies or urease breath test. We first did serological testing.Results: The median age was 55 years (range: 35-76 years), 18 were men (7 women), and the median platelet count was 78×103/μL (range: 6-96×103/μL). The median follow-up durationof this study was 57.57 months. Twenty-three patients had histologically confirmedH. pyloriinfection from UBT or CLO test. All patients experienced complete bacterial eradication. Of these patients, 2 had received immunosuppressive and anti-RhD immunoglobulin treatment beforeH. pylorieradication therapy.Conclusion: It is concluded that H. pylorieradication in ITP patients Leads to significant Improvement of peripheral blood platelet count in most patients.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.003

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.024
GPT teacher head0.238
Teacher spread0.214 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2020
Admission routes1
Has abstractyes

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