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Record W6950549194 · doi:10.5683/sp3/fkx99w

OsterlundJBC_Figure 2

2022· dataset· en· W6950549194 on OpenAlexaff

Bibliographic record

VenueBorealis · 2022
Typedataset
Languageen
Field
Topic
Canadian institutionsUniversity of Toronto
Fundersnot available
KeywordsData setProgrammed cell deathCurve fittingColocalizationBiological dataPrism

Abstract

fetched live from OpenAlex

Figure 2 data Includes: -Panel B, colocalization data. Pearson's correlation values were exported per cell in Cell Profiler, then minimum intensity thresholds were applied to ensure the cells were stained/expressing the protein(s) of interest. Here is the resulting summary where we exported the median and mode of each set of data. -Panel C- F, FLIM-FRET data acquired for one biological replicate acquired where date acquired, Cell line, and mCerulean3-donor is given within each Excel worksheet. Raw binding curve data was binned by Venus intensity. Here we provide the resulting binned data, and fitting parameters exported from GraphPad prism used to create the binding curves that were displayed in the paper. The remaining biological replicates are uploaded with "OsterlundJBC_SFigure 2". -Panel G, Cell death measured in MCF-7 cells and MCF-7 cells expressing mCerulean3-tagged BCL-2 or BCL-XL. Raw data were binned by Venus intensity. Here we provide the resulting binned data from 3 biological replicates, and the fitting parameters exported from GraphPad prism for curves displayed in the paper. -Panel H, Cell death measured in HEK293T cells. AnnexinV positivity is a marker of Cell death. Here we provide the mean cell death measured in Venus positive cells from 3 biological replicates.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesInsufficient payload (model declined to judge)
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Dataset · Consensus signal: none
Teacher disagreement score0.186
Threshold uncertainty score0.265

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0010.002
Bibliometrics0.0020.002
Science and technology studies0.0010.001
Scholarly communication0.0040.003
Open science0.0030.003
Research integrity0.0020.002
Insufficient payload (model declined to judge)0.8140.680

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.021
GPT teacher head0.274
Teacher spread0.253 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; the direct Gemma label and the distilled Codex classifier agree on what is shown here.

Study designNot applicable
Domainnot available
GenreDataset

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2022
Admission routes1
Has abstractyes

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