COVID-19 Infection and Immunity in Residents of Long-term Care Facilities [ C19-IIRLTF, study data contributed to the CITF Databank]
Bibliographic record
Abstract
Background: Long-term care facilities had the highest rate of COVID-19 deaths in Canada; thus, it was essential to understand the effectiveness of vaccines and the risk factors for outbreaks in the elderly residents of long-term care and retirement homes. Aims of the CITF-funded study: This study aimed to 1) understand the association between outbreaks and features of long-term care and retirement homes; 2) determine the recurrence rate of outbreaks in homes that have been previously exposed; 3) describe residents’ immune response to infection and vaccination; and 4) estimate vaccine effectiveness in residents. Methods: This cohort study recruited residents from participating long-term care and retirement home across Ontario through invitations from research coordinators. Study visits occurred at participants’ first dose and second dose of the COVID-19 vaccine, and then 3 weeks, 3 months, 6 months, 9, and 12 months post- second dose. For those who got a third dose, follow up was done 3 weeks, 3 months, and 6 months after their third dose. Staff, essential visitors, and resident participants were followed up every week or per visit for saliva surveillance active COVID infection . A DBS whole blood sample was given at enrolment and at each follow up for serology testing. Contributed dataset contents: The datasets include 1261 participants who completed baseline surveys between January 2021 and July 2023. 90% of participants gave one or more blood samples between April 2021 and April 2023 for analysis. A total of 6078 samples were collected. Variables include data in the following areas of information: demographics (date of birth, sex, race-ethnicity, indigeneity), general health (weight and height, smoking, flu vaccination, chronic conditions), SARS-CoV-2 outcomes (positive test results, hospitalizations), SARS-CoV-2 vaccination, and serology (IgA, IgG, and IgM against SARS-CoV-2 receptor-binding domain (RBD) and spike (S) protein).
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.002 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.001 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.001 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.003 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".