Additional file 1 of Sex differences in the association between marital status and the risk of cardiovascular, cancer, and all-cause mortality: a systematic review and meta-analysis of 7,881,040 individuals
Bibliographic record
Abstract
Additional file 1 Supplemental Table 1. PRISMA 2009 Checklist. Supplemental Table 2. Quality of included studies assessed with Newcastle-Ottawa Scale. Supplemental Table 3. Subgroup analyses of women-to-men ratio of relative risks for all-cause mortality associated with marital status. Supplemental Figure 1. Sex-specific relative risks (RRs) for all-cause mortality, comparing widowed, divorced/separated and never married to married people: (a) Sex-specific RRs for all-cause mortality, comparing widowed to married people; (b) Sex-specific RRs for all-cause mortality, comparing divorced/separated to married people; (c) Sex-specific RRs for all-cause mortality, comparing never married to married people. Supplemental Figure 2. Women-to-men ratios of relative risks (RRRs) for all-cause mortality comparing widowed, divorced/separated and never married to married people: (a) Women-to-men RRRs for all-cause mortality comparing widowed to married people; (b) Women-to-men RRRs for all-cause mortality comparing divorced/separated to married people; (c) Women-to-men RRRs for all-cause mortality comparing never married to married people. Supplemental Figure 3. Sex-specific relative risks (RRs) for cancer mortality, comparing non-married, widowed, divorced/separated and never married to married people: (a) Sex-specific RRs for cancer mortality, comparing non-married to married people; (b) Sex-specific RRs for cancer mortality, comparing widowed to married people; (c) Sex-specific RRs for cancer mortality, comparing divorced/separated to married people; (d) Sex-specific RRs for cancer mortality, comparing never married to married people. Supplemental Figure 4. Women-to-men ratios of relative risks (RRRs) for cancer mortality comparing non-married, widowed, divorced/separated and never married to married people: (a) Women-to-men RRRs for cancer mortality comparing non-married to married people; (b) Women-to-men RRRs for cancer mortality comparing widowed to married people; (c) Women-to-men RRRs for cancer mortality comparing divorced/separated to married people; (d) Women-to-men RRRs for cancer mortality comparing never married to married people. Supplemental Figure 5. Sex-specific relative risks (RRs) for cardiovascular (CV) mortality, comparing non-married, widowed, divorced/separated and never married to married people: (a) Sex-specific RRs for CV mortality, comparing non-married to married people; (b) Sex-specific RRs for CV mortality, comparing widowed to married people; (c) Sex-specific RRs for CV mortality, comparing divorced/separated to married people; (d) Sex-specific RRs for CV mortality, comparing never married to married people. Supplemental Figure 6. Women-to-men ratios of relative risks (RRRs) for cardiovascular (CV) mortality comparing non-married, widowed, divorced/separated and never married to married people: (a) Women-to-men RRRs for CV mortality comparing non-married to married people; (b) Women-to-men RRRs for CV mortality comparing widowed to married people; (c) Women-to-men RRRs for CV mortality comparing divorced/separated to married people; (d) Women-to-men RRRs for CV mortality comparing never married to married people. Supplemental Figure 7. Sex-specific relative risks (RRs) for coronary heart disease (CHD) mortality, comparing non-married, widowed, divorced/separated and never married to married people: (a) Sex-specific RRs for CHD mortality, comparing non-married to married people; (b) Sex-specific RRs for CHD mortality, comparing widowed to married people; (c) Sex-specific RRs for CHD mortality, comparing divorced/separated to married people; (d) Sex-specific RRs for CHD mortality, comparing never married to married people. Supplemental Figure 8. Women-to-men ratios of relative risks (RRRs) for coronary heart disease (CHD) mortality comparing non-married, widowed, divorced/separated and never married to married people: (a) Women-to-men RRRs for CHD mortality comparing non-married to married people; (b) Women-to-men RRRs for CHD mortality comparing widowed to married people; (c) Women-to-men RRRs for CHD mortality comparing divorced/separated to married people; (d) Women-to-men RRRs for CV mortality comparing never married to married people. Supplemental Figure 9. Sex-specific relative risks (RRs) for stroke mortality, comparing non-married, widowed, divorced/separated and never married to married people: (a) Sex-specific RRs for stroke mortality, comparing non-married to married people; (b) Sex-specific RRs for stroke mortality, comparing widowed to married people; (c) Sex-specific RRs for stroke mortality, comparing divorced/separated to married people; (d) Sex-specific RRs for stroke mortality, comparing never married to married people. Supplemental Figure 10. Women-to-men ratios of relative risks (RRRs) for stroke mortality comparing non-married, widowed, divorced/separated and never married to married people: (a) Women-to-men RRRs for stroke mortality comparing non-married to married people; (b) Women-to-men RRRs for stroke mortality comparing widowed to married people; (c) Women-to-men RRRs for stroke mortality comparing divorced/separated to married people; (d) Women-to-men RRRs for stroke mortality comparing never married to married people. Supplemental Figure 11. Meta-regression for mean age at baseline for pooled women-to-men ratios of relative risk for risk of all-cause mortality comparing non-married people to married people. Supplemental Figure 12. Subgroup analyses for all-cause mortality for pooled women-to-men ratios of relative risk (RRRs) for risk of all-cause mortality comparing widowed people to married people. Supplemental Figure 13. Begg’s publication bias plot for the pooled ratio of women-to-men relative risks: (a) Begg’s publication bias plot for CHD mortality in divorced/separated group; (b) Begg’s publication bias plot for all-cause mortality in widowed group; (c) Begg’s publication bias plot for all-cause mortality in never married group; Abbreviations: CHD: coronary heart disease; RR: relative risk; RRR: ratio of RR.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.003 | 0.041 |
| Meta-epidemiology (narrow) | 0.002 | 0.001 |
| Meta-epidemiology (broad) | 0.003 | 0.005 |
| Bibliometrics | 0.004 | 0.007 |
| Science and technology studies | 0.001 | 0.000 |
| Scholarly communication | 0.002 | 0.003 |
| Open science | 0.002 | 0.001 |
| Research integrity | 0.002 | 0.001 |
| Insufficient payload (model declined to judge) | 0.727 | 0.030 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".