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Record W6958222989 · doi:10.6084/m9.figshare.16599642

Additional file 7 of Pathologic tau conformer ensembles induce dynamic, liquid-liquid phase separation events at the nuclear envelope

2021· article· en· W6958222989 on OpenAlexaff

Bibliographic record

VenueFigshare · 2021
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicNuclear Structure and Function
Canadian institutionsUniversity of Alberta
Fundersnot available
KeywordsCompartmentalization (fire protection)FluorescenceTransfectionEnvelope (radar)Conformational isomerismPhase (matter)Green fluorescent proteinScale (ratio)

Abstract

fetched live from OpenAlex

Additional file 7: Supplementary Figure 7. Nuclear-cytoplasmic compartmentalization in ES1 cells. Control reporter cells (a) and ES1 cells (b) were transiently transfected with nuclear-cytoplasmic compartmentalization (NCC) reporter construct and imaged at 24 hours post transfection. The images were obtained from 8 different areas (160 μm2 for each), respectively. Faint dispersed (in the control) and strong aggregated tau signals (in ES1) were often overlapped with green fluorescent protein (GFP) signals derived from the NCC reporter. RFP, red fluorescent protein (in magenta). Scale bar, 20 μm.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesInsufficient payload (model declined to judge)
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Dataset · Consensus signal: Dataset
Teacher disagreement score0.942
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.9430.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.015
GPT teacher head0.263
Teacher spread0.248 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; both teacher heads agree on what is shown here.

Study designNot applicable
Domainnot available
GenreDataset

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2021
Admission routes1
Has abstractyes

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