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Record W6958346663 · doi:10.6084/m9.figshare.26986453

Additional file 1 of Astrocytes display ultrastructural alterations and heterogeneity in the hippocampus of aged APP-PS1 mice and human post-mortem brain samples

2024· other· en· W6958346663 on OpenAlexaff

Bibliographic record

VenueFigshare · 2024
Typeother
Languageen
FieldEnvironmental Science
TopicPeatlands and Wetlands Ecology
Canadian institutionsMcGill UniversityUniversity of British ColumbiaUniversité LavalUniversity of Victoria
Fundersnot available
KeywordsAxonAstrocyteHippocampal formationPhagosomeDendritic spineUltrastructureHippocampus

Abstract

fetched live from OpenAlex

Additional file 1: Figure S1. A blood vessel-associated dark astrocyte imaged serially distances displays several phagosomes. In A–A″, pictures of a dark astrocyte taken serially at a distance of 5–6 µm were acquired. The dark astrocytic cell body, associated with a blood vessel, shows numerous contacts with dendritic spines (pseudo-colored in orange) and axon terminals (pseudo-colored in blue) and contains several partially digested phagosomes (pseudo-colored in purple), notably axon terminals and dendritic spines. Yellow = nuclear membrane, red pseudo-coloring = blood vessel, orange pseudo-coloring = dendritic spine, blue pseudo-coloring = axon terminals, green pseudo-coloring = mitochondria, purple pseudo-coloring = partially digested phagosomes

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.016
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.876
Threshold uncertainty score0.177

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.016
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0020.003
Science and technology studies0.0010.000
Scholarly communication0.0020.002
Open science0.0020.001
Research integrity0.0020.001
Insufficient payload (model declined to judge)0.8760.256

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.013
GPT teacher head0.238
Teacher spread0.225 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2024
Admission routes1
Has abstractyes

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