MétaCan
Menu
← Back to cohort
Record W6966387955 · doi:10.48336/ncw2-1w46

Duty to warn for genetic testing: the importance of understanding harm when practically applying The president's commission standards of disclosure

2021· article· en· W6966387955 on OpenAlexaff

Bibliographic record

VenueMemorial University Research Repository (Memorial University) · 2021
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicBRCA gene mutations in cancer
Canadian institutionsMemorial University of Newfoundland
Fundersnot available
KeywordsHarmDuty to warnDilemmaObligationMistakeDutyConfidentialityHealth careFace (sociological concept)

Abstract

fetched live from OpenAlex

The field of genetics is unique as test results reveal information about multiple individuals. When a hereditary condition is identified, healthcare professionals face an ethical dilemma between their duty of confidentiality toward their patients and their moral obligation to warn relatives of possible harm. The standards developed by The 1983 President's Commission1 guide healthcare professionals with this decision-making process. This thesis will argue that these standards of disclosure are defensible in the face of common criticisms of genetic information disclosure and are a good guide for health care professionals challenged with this ethical dilemma. However, there are challenges when practically applying these standards because of the standards’ reliance on the notion of harm. Harm is complex, and when using the standards, we must distinguish between a harmful action and a wrongful action. This thesis will argue that this distinction must be made when practically applying these standards to avoid a mistake in our understanding of the situation. An improper understanding would result in a moral dilemma as the rights of another would be infringed upon in an unjustified manner.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.182
metaresearch head score (Gemma)0.291
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: Theoretical or conceptual
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.182
Threshold uncertainty score0.960

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.1820.291
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0020.001
Bibliometrics0.0030.002
Science and technology studies0.0120.066
Scholarly communication0.0290.026
Open science0.0050.012
Research integrity0.0330.040
Insufficient payload (model declined to judge)0.0020.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.072
GPT teacher head0.321
Teacher spread0.249 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designTheoretical or conceptual
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2021
Admission routes1
Has abstractyes

Explore more

Same venueMemorial University Research Repository (Memorial University)→Same topicBRCA gene mutations in cancer→French-language works237,207→