Psychological and Behavioral Abnormalities as the Initial Manifestation of Idiopathic Hypoparathyroidism: A Case Report
Bibliographic record
Abstract
Background Idiopathic hypoparathyroidism is a rare endocrine disorder typically manifesting as paresthesias of the extremities and perioral region, muscle cramps, capopedal spasms, tetany, seizure, and fatigue. The condition is not known to manifest initially as psychological and behavioral abnormalities. Case presentation We report the case of a 53-year-old Chinese woman who presented with symptoms of depression, anxiety, feelings of agitation, irritability, hyperhidrosis, slow action and decreased interest in most activities. Computed tomography of the brain revealed intracranial calcification, scores on the Hamilton Anxiety Scale and Hamilton Depression Scale showed that she suffered from depression and anxiety, and scores on the Minimum Mental State Examination and Montreal Cognitive Assessment revealed impaired cognitive function. Laboratory analyses showed hypocalcemia, hyperphosphatemia and parathyroid hormone deficiency. Calcium carbonate and vitamin D3 supplementation therapy improved the patient’s clinical symptoms of depression and anxiety, as well as her levels of calcium and phosphate. However, this treatment did not substantially improve the level of parathyroid hormone or reduce cognitive impairment. Conclusions Idiopathic hypoparathyroidism can manifest initially as psychological and behavioral abnormalities, which clinicians should keep in mind.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.001 | 0.001 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".