Additional file 5 of Deficits in coordinated neuronal activity and network topology are striatal hallmarks in Huntington’s disease
Bibliographic record
Abstract
Additional file 5: Figure S5. Quantification of individual spontaneous activity in WT and HD striatal and cortical primary cultures. (A-E) Single neuron statistics. (A) Activity rate, i.e., average spikes per second of each neuron. (B) Inter-spike interval (ISI), i.e., average time between two consecutive spikes. (C) Bursting rate, i.e., frequency of single-cell bursts. (D) Average inter-burst interval (IBI), average time between consecutive individual bursts (STR WT n=38; STR HD n=37; CTX WT n= 19; CTX HD n=22). Each dot represents a single experiment, thick line the mean, thick shaded area the Standard Error of the Mean and thin shaded area the standard deviation. Statistical analysis was performed using Student t-test. * p< 0.05, ** p<0.01 compared to WT.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.024 |
| Meta-epidemiology (narrow) | 0.001 | 0.001 |
| Meta-epidemiology (broad) | 0.002 | 0.001 |
| Bibliometrics | 0.002 | 0.003 |
| Science and technology studies | 0.001 | 0.000 |
| Scholarly communication | 0.002 | 0.002 |
| Open science | 0.002 | 0.001 |
| Research integrity | 0.002 | 0.001 |
| Insufficient payload (model declined to judge) | 0.909 | 0.177 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".