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Additional file 5 of Deficits in coordinated neuronal activity and network topology are striatal hallmarks in Huntington’s disease

2020· article· en· W6976382457 on OpenAlexaff

Bibliographic record

VenueFigshare · 2020
Typearticle
Languageen
FieldPhysics and Astronomy
TopicExperimental and Theoretical Physics Studies
Canadian institutionsUniversity of Calgary
Fundersnot available
KeywordsBurstingInterval (graph theory)Premovement neuronal activityNetwork topologyTopology (electrical circuits)NeuronLine (geometry)Statistical analysis

Abstract

fetched live from OpenAlex

Additional file 5: Figure S5. Quantification of individual spontaneous activity in WT and HD striatal and cortical primary cultures. (A-E) Single neuron statistics. (A) Activity rate, i.e., average spikes per second of each neuron. (B) Inter-spike interval (ISI), i.e., average time between two consecutive spikes. (C) Bursting rate, i.e., frequency of single-cell bursts. (D) Average inter-burst interval (IBI), average time between consecutive individual bursts (STR WT n=38; STR HD n=37; CTX WT n= 19; CTX HD n=22). Each dot represents a single experiment, thick line the mean, thick shaded area the Standard Error of the Mean and thin shaded area the standard deviation. Statistical analysis was performed using Student t-test. * p< 0.05, ** p<0.01 compared to WT.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Dataset · Consensus signal: none
Teacher disagreement score0.945
Threshold uncertainty score0.368

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.8050.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.014
GPT teacher head0.225
Teacher spread0.211 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designNot applicable
Domainnot available
GenreDataset

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2020
Admission routes1
Has abstractyes

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