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Additional file 2 of An in vitro bioengineered model of the human arterial neurovascular unit to study neurodegenerative diseases

2020· article· en· W6976695950 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueFigshare · 2020
Typearticle
Languageen
FieldSocial Sciences
TopicOnline Learning Methods and Innovations
Canadian institutionsUniversity of British Columbia
Fundersnot available
KeywordsNeurovascular bundleIn vitroImmunostainingLumen (anatomy)Permeability (electromagnetism)Arterial wall

Abstract

fetched live from OpenAlex

Additional file 2: Supplemental Figure 2. Histological characterization and function of bioengineered arterial NVU. a) The histological structure of the arterial NVU was assessed by H&E staining. b) The astrocytes in arterial NVU were further analyzed with immunostaining against aquaporin 4 (AQ4). Barrier integrity was assessed by measuring permeability of 250 μg/ml of 4 kDa FITC-dextran circulated through the lumen for 2 h. Points in graphed data represent individual bioengineered vessels, bars represent mean, error bars represent ±SEM. ABL = antelumen.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.005
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Dataset · Consensus signal: none
Teacher disagreement score0.600
Threshold uncertainty score0.543

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.005
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.6000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.093
GPT teacher head0.343
Teacher spread0.249 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it