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The long-distance movements of organelles identified as lipid bodies in hyphae of Rhizopus arrhizus are highly organized and occur along intracellular tracks.

2020· article· en· W6977222919 on OpenAlexaboutno aff

Bibliographic record

VenueFigshare · 2020
Typearticle
Languageen
FieldSocial Sciences
TopicHealth, Education, and Cultural Studies
Canadian institutionsnot available
Fundersnot available
KeywordsOrganelleCytoplasmIntracellularHyphaCytoplasmic streamingMicrotubuleLipid dropletVesicle

Abstract

fetched live from OpenAlex

Nutrient translocation in fungal mycelia has often been connected with cytoplasmic organelle movements. If these movements partake in nutrient translocations, they should occur over long distances within the fungal mycelium and even at long distances from the growing fungal tips. Light microscopy techniques in combination with digital image processing make it possible to study organelle movements in relatively large mycelia of <i>Rhizopus arrhizus</i> under undisturbed conditions in a closed plastic Petri dish. The movements seen under these conditions resemble long distance movement of vesicles by fast axonal transport in neurons, or organelle movements in the giant internodal cells of characean algae. The organelles follow specific paths in both directions through the main hyphae and in and out of hyphal branches and appear to connect mycelial parts several centimeters apart. The organelle velocity was between 0.9-6.6 mm s<sup>-1</sup> with an average of 3.7 mm s<sup>-1</sup>. The speed, pattern of movement and the inhibition of the movement with nocodazole indicate that microtubules are involved in the locomotion along the intracellular paths. The most prominent moving organelles were identified as lipid bodies as they were heavily stained by the organelle specific vital fluorescent dye, Nile Red. On the other hand, mitochondria were lying still and often seen lined up along the intracellular paths of movement of the other organelles when visualized by the mitochondria specific vital fluorescent dye DiOC<sub>7</sub>(3). Thus, an active translocation of lipid bodies along the intracellular paths might be responsible for carbon translocation. It is also discussed how this translocation might be directly involved in the energy homeostasis of the studied fungus.Linked under References is a short clip showing the ordered movements of organelles in an undisturbed hypha under undisturbed conditions. First shown in normal speed then 5 times faster to help our eyes to see that the organelles follows distinct paths and organelles travels on the same paths in both directions.<br>Comment: Part of this work was originally presented as a poster at Fifth International Mycological Congress, Vancouver, BC, Canada, August 14 - 21, 1994.<br>It is now made available as a preprint in its 1998 version since colleagues have asked for the data. The work was not published then since reviewers had problems accepting both digital images and image processing in Science since they still regarded photo and film as "objective and unbiased" observations. Using digital techniques to make things visible that the eyes cannot see was suspect.<br>NOTE: This preprint can be cited but citation year should be 1998 since the citations and the discussion has not been updated. Anyone thinking this work is worth publishing with peer review should feel free to help me update it. Contact me first and I will then make you first author for the submission if you are interested.Email: stefan@olssonstefan.com<br>

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.002
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Qualitative · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.401
Threshold uncertainty score0.997

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0010.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0040.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.037
GPT teacher head0.292
Teacher spread0.255 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designQualitative
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2020
Admission routes1
Has abstractyes

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