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Record W6977294438 · doi:10.6084/m9.figshare.12028197

Additional file 2 of Activation of the PDGFRα-Nrf2 pathway mediates impaired adipocyte differentiation in bone marrow mesenchymal stem cells lacking Nck1

2020· article· en· W6977294438 on OpenAlexaff

Bibliographic record

VenueFigshare · 2020
Typearticle
Languageen
FieldComputer Science
TopicComputer Graphics and Visualization Techniques
Canadian institutionsMcGill University Health Centre
Fundersnot available
KeywordsMesenchymal stem cellAdipocyteOil Red OBone marrowStem cellMessenger RNACellular differentiationAdipose tissue

Abstract

fetched live from OpenAlex

Additional file 2: Figure S2. Effects of Nck1 depletion in mesenchymal stem cells. (A) Representative images (DIC, 10X) and Oil red O staining in day 5 differentiated siControl and siNck1 C3H10T1/2 cells (n=3/group). (B) Relative Pparg, Fabp4, Adipoq, and Nck1 mRNA levels before (black bars) and at day 7 of differentiation (white bars) in siControl and siNck1 C3H10T1/2 cells (n=3/group). (C) Relative Pdgfa and Pdgfc mRNA levels in siControl and siNck1 C3H10T1/2 cells (n=5-6/group). Data are mean ± SEM. Statistical significance evaluated by unpaired Student’s t-test is reported as *p≤0.05, and **p≤0.01.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.018
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesInsufficient payload (model declined to judge)
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Other · Consensus signal: none
Teacher disagreement score0.079
Threshold uncertainty score0.113

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.018
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0020.001
Bibliometrics0.0020.003
Science and technology studies0.0010.000
Scholarly communication0.0020.002
Open science0.0030.001
Research integrity0.0020.001
Insufficient payload (model declined to judge)0.9210.223

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.032
GPT teacher head0.229
Teacher spread0.197 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; the direct Gemma label and the distilled Codex classifier agree on what is shown here.

Study designNot applicable
Domainnot available
GenreOther

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2020
Admission routes1
Has abstractyes

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