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Record W6980436757

Cardiorespiratory modifications, and limitations, in growth hormone transgenic Atlantic salmon (Salmo salar)

2005· dissertation· en· W6980436757 on OpenAlexfundno aff

Bibliographic record

VenueMemorial University Research Repository (Memorial University) · 2005
Typedissertation
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicPlant-derived Lignans Synthesis and Bioactivity
Canadian institutionsnot available
FundersNatural Sciences and Engineering Research Council of Canada
KeywordsCardiorespiratory fitnessTransgeneCatecholamineHeart rateMetabolic rateGrowth rateGrowth hormoneHormone
DOInot available

Abstract

fetched live from OpenAlex

GH transgenic Atlantic salmon transgenic grew 3.6x faster than non-transgenic controls, and most aspects of their cardiorespiratory system were upregulated. For example, they had greater resting and post-stress catecholamine levels, higher post-stress haemoglobin concentrations, increased maximum heart performance, and elevated aerobic enzyme activities. However, they had a higher routine metabolic rate without a change in maximum metabolic rate (M02111ax), resulting in a decreased metabolic scope, and subsequently a lowered critical swimming speed. Overall, this study supports the theory of symmorphosis, in that most aspects of the transgenic's cardiorespiratory system are upregulated to accommodate the additional demands of higher growth and/or activity. However, the transgenics MO2max appears to be limited by their gill surface area, which was not upregulated. Further, it provides information on "their physiology that can be used to: 1) understand their needs in an aquacultural setting; and 2) infer the possible ecological consequences of their escape.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.003
Threshold uncertainty score0.007

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.030
GPT teacher head0.245
Teacher spread0.214 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2005
Admission routes1
Has abstractyes

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