Fusarium mycotoxicoses in poultry and swine: a comparative study of characterization and prevention
Why this work is in the frame
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
Bibliographic record
Abstract
Deoxynivalenol (DON, vomitoxin), zearalenone and fusaric acid are the most commonly found 'Fusarium' mycotoxins in Ontario-grown feedstuffs. Trials were conducted to compare the effects of feeding diets naturally-contaminated with 'Fusarium' mycotoxins on broiler chickens and starter pigs. The contaminated diets were formulated by replacing corn and wheat of the control diet with those naturally-contaminated with ' Fusarium' mycotoxins. A polymeric glucomannan mycotoxin adsorbent (GM polymer) was also tested for its ability to prevent 'Fusarium' mycotoxicoses. Starter pigs were fed approximately half the amount of contaminated grains compared to broiler chickens. Feed intake and weight gain in pigs fed contaminated grains was reduced by 32 and 34%, respectively, while the decreases in broiler chickens were 15 and 12%. There is strong evidence that serotonergic and [alpha]2-noradrenergic systems interact antagonistically through medial hypothalamic satiety mechanisms. Serotonergic neurotransmitter concentrations were elevated, while norepinephrine concentrations decreased in the brain of pigs fed contaminated grains. The lack of an antagonistic interaction of these two systems on feed intake might explain feed refusal in pigs. In contrast, both norepinephrine and serotonergic neurotransmitter concentrations were elevated in broiler chickens, thus permitting the possible antagonistic interaction between the two systems. This situation may explain the less severe feed refusal seen in broiler chickens. The feeding of contaminated grains increased serum IgA and IgM concentrations in pigs, but not in broiler chickens. Peripheral blood monocyte and B cell numbers were decreased in chickens fed contaminated grains but not in pigs. The feeding of contaminated diets did not significantly alter contact hypersensitivity and antibody response. It was concluded that the changes in the number of peripheral blood immune cells were more prominent in broiler chickens than in starter pigs, but this was not enough to alter antibody and cell-mediated immune responses. Glucomannan polymer was able to prevent some of the adverse effects of 'Fusarium' mycotoxins on serum immunoglobulin concentrations, brain regional neurotransmitter concentrations, serum chemistry and hematology. It was, however, unable to prevent 'Fusarium' mycotoxin-induced reduction in feed intake and weight gains at the levels of inclusion of contaminated grains in the current studies.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it