Measurement of oligomerization states of membrane proteins via spatial fluorescence intensity fluctuation analysis
Bibliographic record
Abstract
List of Figures 4.10 Plots of the results of spatial high order moment analysis applied to CLSM images of 2D samples of Green and red fluorescent beads. . . .4.11 Plots of the results of spatial high order moment analysis applied to CLSM images of 2D samples of Orange and red fluorescent beads. . .4.12 CLSM images of Alexa Fluor R 488 SDP ester conjugate covalently bound to glass coverslip surfaces. . . . . . . . . . . . . . . . . . . . .4.13 The calibration curve of measured 2D coverslip surface density of Alexa Fluor R 488 SDP ester conjugate as a function of dye concentration in 3D solution. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .4.14 Quantal brightness of Alexa Fluor R 488 measured for 2D samples prepared with different values of concentration in 3D solution. . . . .4.15 The effect of irreversible photobleaching on the quantal brightness and density of Alexa Fluor R 488 recovered from the moment analysis and SpIDA. . . . . . . . . . . . . . . . . .
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.001 |
| Meta-epidemiology (narrow) | 0.001 | 0.001 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.001 | 0.000 |
| Research integrity | 0.001 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".