Alpha EEG Spectral Characteristics in the Parieto-Occipital lobe of Elderly Patients with Chronic Insomnia and Mild Cognitive Impairment
Bibliographic record
Abstract
ObjectiveAnalysis of Alpha Spectral Characteristics in the Parieto-Occipital lobe of Elderly Individuals with Chronic Insomnia and Mild Cognitive Impairment （MCI）.MethodsEighty elderly individuals with chronic insomnia and mild cognitive impairment （MCI） were selected from the community in Fuzhou, Fujian Province, from June 2019 to December 2020. This included a healthy control group （HC） of30 individuals, a chronic insomnia group （CI） of 20 individuals, and a chronic insomnia with MCI group （CI-MCI） of 30 individuals. The Pittsburgh Sleep Quality Index （PSQI） was used to assess sleep quality, while the Fuzhou version of the Montreal Cognitive Assessment （MoCA） was employed to evaluate cognitive functions, including visuospatial execution, naming, attention, verbal fluency, abstraction, delayed recall, and orientation. Daytime resting-state electroencephalography （EEG） was collected using the Neuroscan synchronous EEG recording system, comparing the power values and trends of alpha waves （8–13 Hz） across channels in the occipital lobe. Additionally, we analyzed the changes in alpha spectral power in relation to cognitive functions.Results（1）PSQI scores：Compared to the HC group, the daytime functional impairment scores in the CI-MCI group were significantly higher, with a statistically significant difference （P <0. 05）. The total PSQI scores, sleep quality, sleep onset latency, total sleep time, sleep efficiency, and sleep disturbance scores were significantly higher in the CI group and the CI-MCI group, while the use of hypnotics score was significantly reduced, with statistically significant differences （P <0. 05）. （2）MoCA scores：Compared to the HC and CI groups, the CI-MCI group exhibited significantly lower total MoCA scores, as well as reductions in visuospatial execution, naming, attention, verbal fluency, delayed recall, and orientation, with statistically significant differences （P <0. 05）. （3）EEG spectral characteristics：Compared to the HC group, the CI-MCI group showed significantly increased alpha spectral power at sites P1, P6, POZ, PO4, and PO6 in the Parieto-Occipital lobe, with statistically significant differences （P <0. 05）. Additionally, the topographical maps of the alpha spectral power in the parietal and occipital lobes were notably stronger in the CI-MCI group compared to the HC group. （4）Correlation between changes in occipital alpha spectral power and cognitive function：The alpha spectral power at site P6 in the right parietal lobe （r =0. 444, P =0. 023）, at site POZ in the occipital lobe （r =0. 444, P =0. 023）, and at site PO4 in the right parietal lobe （r =0. 478, P =0. 014） all showed a positive correlation with visuospatial executive function.ConclusionThe changes in Parieto-Occipital lobe alpha spectral power are indicative of cognitive impairment in elderly individuals with chronic insomnia and mild cognitive impairment （MCI）. Moreover, Parieto-Occipital lobe alpha spectral power can modulate cognitive function in this population.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".