Modifiability of residual force depression in single muscle fibres following uphill and downhill training in rats
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Bibliographic record
Abstract
Following active muscle shortening, steady-state isometric force is less than a purely isometric contraction at the same muscle length and level of activation; this is known as residual force depression (rFD). The purpose of this thesis was to investigate whether rFD in single muscle fibres is modifiable through downhill and uphill running in the extensor digitorum longus (EDL) and soleus (SOL) muscles in rats. Rats were randomly assigned to either a control or intervention group, where they were run uphill or downhill 5 days/wk for 4 wks. rFD was present for both the EDL (6-15%) and SOL (1-2%), with no effect of training. rFD was greater for the EDL than SOL which closely corresponded to the greater work of shortening and stiffness depression in the EDL. These results indicate that while rFD was observed, training did not appear to alter this intrinsic history-dependent property of single muscle fibres.
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Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
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Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
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