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Record W6997326405

Variation in immune response and survival between purebred holstein and crossbred norwegian red X holstein calves and first calf heifers

2010· dissertation· en· W6997326405 on OpenAlexaboutno aff

Bibliographic record

VenueThe Atrium (University of Guelph) · 2010
Typedissertation
Languageen
FieldVeterinary
TopicAnimal health and immunology
Canadian institutionsnot available
Fundersnot available
KeywordsPurebredCrossbreedImmune systemAntibodyHerdAntibody response
DOInot available

Abstract

fetched live from OpenAlex

This study evaluated immune response and survival between Holstein and Norwegian Red X Holstein calves and first calf heifers. Two to six month old calves and heifers were bled and immunized with type 1 and type 2 antigens. Antibody responses were evaluated using enzyme-linked immunosorbant assay. Delayed-type hypersensitivity was used as an indicator of cell-mediated immune response and proportions of leukocyte populations were evaluated using differentials and flow cytometry. Survival data was provided by CanWest Dairy Herd Improvement (Guelph, Ont.). Ail data were analyzed using general liner models. Crossbred calves and heifers had greater survival and primary antibody response. Crossbred heifers also had greater proportions of lymphocytes, delayed-type hypersensitivity and type 1 and type 2 antibody responses based on antibody isotype response. Purebred heifers had greater proportions of monocytes. Therefore crossbreds may have increased disease resistance due to enhanced immune responses and this may play a role in increasing survival.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.007
Threshold uncertainty score0.013

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.025
GPT teacher head0.272
Teacher spread0.247 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2010
Admission routes1
Has abstractyes

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