Structural and functionnal [sic] consequences of oxygen induced retinopathy
Bibliographic record
Abstract
Retinopathy of prematurity (ROP) is a potentially blinding retinal disorder, which results from the exposure of the premature infant to hyperoxia. The diagnosis and the assessment of severity of ROP are based on the degree of retinal vascular abnormalities (such as avascular peripheral retina and neovascularisation), which are observed upon fundus examination. However, even if the vascular consequences of ROP are resolved, functional sequels such as high myopia, anisometropia and strabismus, may persist through adulthood. In severe cases, even more dramatic consequences, namely retinal detachment and blindness, may also occur. In oxygen-induced retinopathy (OIR), the animal model of ROP, hyperoxia-induced vasoobliteration and neovascularisation have been studied extensively in mice, rats, cats and dogs. However, the functional and ultrastructural changes that might result from the exposure to hyperoxia have not yet been examined in details. In this study, we report functional, as assessed with the electroretinogram (ERG), and structural, determined with histological sections of the retina, consequences of postnatal hyperoxia which took place during a period of intense retinal maturation, that is, the first 14 days of life of Sprague Dawley rats.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.002 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".