Colistin non-susceptible Pseudomonas aeruginosa ST654 with blaNDM-1 arrives in North America
Why this work is in the frame
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
Bibliographic record
Abstract
This study describes 3 different blaNDM-1 genetic platforms in 3 different species obtained from \nthe same patient who was directly transferred to an institution in Calgary, Canada, following a \nprolonged hospital stay in India. The blaNDM-1 in the Escherichia coli was located on a 176kb \nIncA/C plasmid contained within an ISCR1 region. The blaNDM-1 in the Providencia rettgeri was \nlocated on a 117kb IncT plasmid contained within Tn3000, while the blaNDM-1 in Pseudomonas \naeruginosa was located on the chromosome within an ISCR3 region. This report highlights the \nplasticity of the genetic regions and environments associated with blaNDM-1. To the best of our \nknowledge, this is the first report of P. aeruginosa with blaNDM-1 identified in North America and \nthe first report of blaOXA-181in P. rettgeri. The P. aeruginosa belonged to the international high \nrisk clone ST654 and was non-susceptible to colistin. This case emphasizes the need for \nappropriate infection prevention and control measures and vigilant screening for carbapenem \nresistant Gram negative bacteria in patients with a history of travel to endemic areas, such as the \nIndian subcontinent.
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.001 | 0.001 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.000 | 0.002 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.001 | 0.000 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.001 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it