Nuclear encoded RNA maturases of «Arabidopsis thaliana»
Bibliographic record
Abstract
Group II introns are a family of introns found in bacterial and organellar, but not in nuclear genomes. Many group II introns encode proteins termed maturases which are required for their splicing and retrotransposition. Recently four maturase-like proteins were identified in the Arabidopsis thaliana nuclear genome. The proteins encoded by these genes are termed nuclear maturases (NMATs). The four NMAT proteins are classified as NMAT1A, NMAT1B, NMAT2A, and NMAT2B. Nuclear maturases are predicted to have mitochondrial localization signals and a conserved X domain suggesting that these putative maturases are transported to organelles and may function in splicing of group II introns. My results indicate that NMAT1A, NMAT2A, and NMAT2B are all required for embryo viability. Analysis of mitochondrial transcripts from the mutant plants indicate that NMAT2A is necessary for efficient splicing of intron 1 of the nad2 gene, and that NMAT2A is necessary for efficient splicing of intron 1 of the nad5 gene. The results thus confirm the hypothesis that NMATs are required for the specific efficient splicing of mitochondrial transcripts.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.004 | 0.002 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".