Investigating biological and social factors influencing the HIV epidemic in Manitoba
Bibliographic record
Abstract
Host factors can have important consequences for HIV risk and disease progression. Two separate projects relevant to Aboriginal populations in Manitoba were undertaken. The Solvent Use Project investigated solvent use in Winnipeg through an interdisciplinary multi-phase approach that integrated community based research and basic science. From interviews with solvent users and key informants we learned that solvent users experience many health and social disparities. We demonstrated that there is support within the community to work with solvent users and study solvent use further. The HLA-B*35 Project aimed to identify the diversity of HLA-B*35 allele subtypes, in HIV+ patients that presented to care between 2007 and 2010 in Manitoba. We observed 11 distinct HLA-B*35 allele subtypes. Case studies reflected the overrepresentation of Aboriginal people infected with HIV in Manitoba, and the pressing issues of either late presentation to care or rapid disease progression within patients who are HLA B*35.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.002 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.002 | 0.003 |
| Science and technology studies | 0.007 | 0.001 |
| Scholarly communication | 0.002 | 0.000 |
| Open science | 0.001 | 0.002 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.002 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".