Résultat du programme de dépistage clinique, échocardiographique et Doppler des sténoses aortiques et pulmonaires chez le Terre-Neuve et le Landseer en France : 756 cas entre 2010 et 2021
Bibliographic record
Abstract
Newfoundland and Landseer are predisposed to congenital arterial stenoses, particularly aortic stenosis (STAo). Tight arterial stenoses generally have a poor short-term prognosis, despite current surgical and medical treatment options. An arterial stenosis screening protocol was implemented by the Breed Club in 2010 to regulate the occurrence of these heart diseases. The purpose of the study performed was to analyze the different epidemiological information related to this screening between 2010 and 2021 and to study the subpopulation of dogs with arterial stenosis. A total of 756 dogs participated in the protocol thanks to 114 veterinarians, including 10 veterinarians specializing in cardiology (8.8%), distributed in 55 departments of metropolitan France. The median age of the dogs at the time of screening was 1.9 years (IQR interquartile range : 1.6-2.7) for a female:male ratio of 1.8, with no sexual predisposition to the occurrence of STAo. Of the 756 dogs in the protocol, the percentage of those affected was 1.12% (8 dogs) for STAo and 0.27% (2 dogs) for STAP. Only Newfoundland dogs had stenosis in this study ; no Landseer in the protocol was diagnosed with STAo or STAP. More than 90% of the dogs in the study required only a single examination to reach a diagnosis of stenosis, and the ability to detect murmurs, including low-grade murmurs, was similar between veterinarians (specialists and non-specialists). The SSBG murmur present in animals with STAo was also found in 5/691 (0.72%) dogs free of stenosis. The location of the aortic stenotic obstruction in STAo was predominantly subvalvular (75%) and no supravalvular stenosis was diagnosed. The median (interquartile range) maximum transaortic flow velocity (Vmax) in dogs free of any heart disease was 1.75 (1.59 to 1.93) m/s, whereas it was 3.06 (2.67 to 3.21) m/s for animals diagnosed as ""AS1."" No significant association between the presence of STAo and coat, inbreeding coefficient and diagnosis for hip and elbow dysplasia was found. In conclusion, the large number of veterinarians who participated in the screening protocol, especially the large proportion of non-specialist veterinarians, shows that this examination can be routinely performed in practice. The high rate of definitive diagnoses on first examination and the effective detection of murmurs reinforce this statement. In order to make screening more accessible throughout France, it would be interesting to develop it in new departments by making veterinarians aware of the ease of setting up and performing the protocol, including for non-specialist veterinarians. Particular importance should be placed on cardiac auscultation, taking care not to over diagnose stenoses when the dog has SSBG. Although the Newfoundland is still one of the breeds predisposed to STAo, the implementation of this screening protocol on a large scale in France could eventually decrease the proportion of affected dogs.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.011 | 0.005 |
| Meta-epidemiology (narrow) | 0.001 | 0.001 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.001 | 0.001 |
| Open science | 0.001 | 0.000 |
| Research integrity | 0.000 | 0.002 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".