Trends in dispensed opioid analgesics in Quebec, Canada 1994-2007
Why this work is in the frame
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
Bibliographic record
Abstract
To identify patient sub-groups with changes in opioid analgesic use in Quebec between 1994 and 2007, a cohort of 2 698 624 adult patients with public drug insurance was assembled.Time series analysis was used to examine both the proportion of patients each day with an opioid prescription and mean daily dose of opioid prescriptions.Analyses were stratified by patient and opioid characteristics.Daily prevalence of opioid use rose from 0.6% to 1.6% in noncancer patients and 1.5% to 3.7% in cancer patients between 1994 and 2007.Mean daily opioid dose more than tripled in non-cancer patients, due to increasing simultaneous use of both long and short-acting opioids.Patients 80 and older showed the greatest relative increase in opioid use, with fentanyl patch adopted more rapidly in this age group than any other.Further research should evaluate beneficial and adverse effects associated with the increasing use of opioids in non-cancer patients.Trends in Opioid Use Kristen Reidel iii Abrg Pour dterminer les sous-groupes de patients pour lesquels l'utilisation d'analgsiques opiodes a chang au Qubec entre 1994 et 2007, une cohorte de 2 698 624 patients adultes couverts par le rgime public d'assurance mdicaments a t cre.Un analyse de sries chronologiques a t utilise pour calculer la proportion quotidienne de patients sous opiodes et la dose quotidienne moyenne d'opiodes.Toutes les analyses ont t stratifies selon les caractristiques des patients et les caractristiques des opiodes.Entre 1994 et 2007, la frquence quotidienne de consommation d'opiodes est passe de 0,6% 1,6% chez les patients non cancreux et de 1,5% 3,7% chez les patients cancreux.La dose quotidienne moyenne d'opiodes a plus que tripl chez les non cancreux, en raison de l'augmentation de l'utilisation des opiodes longue dure d'action associe aux opiodes courte dure d'action.Les patients gs de plus de 80 ans ont montr la plus forte augmentation relative de consommation d'opiodes, et le fentanyl a t adopt plus rapidement dans cette tranche d'ge que dans les autres.D'autres recherches devraient permettre d'valuer les impacts positifs et ngatifs de cette augmentation de l'utilisation d'opiodes chez les patients non cancreux.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.000 |
| Meta-epidemiology (narrow) | 0.001 | 0.001 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.001 | 0.002 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.001 |
| Open science | 0.002 | 0.000 |
| Research integrity | 0.001 | 0.003 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it