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Record W7037412300

Effects of Various Molecules on the Structure and Dynamics of Lipid Membranes

2015· article· en· W7037412300 on OpenAlexfundno aff

Bibliographic record

VenueScience and Technology Facilities Council · 2015
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicLipid Membrane Structure and Behavior
Canadian institutionsnot available
FundersBasic Energy SciencesNatural Sciences and Engineering Research Council of CanadaNational Research Council CanadaOntario Ministry of Economic Development and InnovationStrongU.S. Department of EnergyMinistero dello Sviluppo EconomicoNational Science Foundation
KeywordsDynamics (music)MembraneMoleculeLipid bilayerPhospholipid
DOInot available

Abstract

fetched live from OpenAlex

Hydration Water Freezing in Single Supported Lipid Bilayers" and the two-dimensional diffusion dynamics of the hydration water of solid-supported, stacked bilayers in the submission "Anomalous and Anisotropic Nanoscale Diffusion of Hydration Water in Fluid Lipid Membranes".Chapter 5 introduces the effect of the ubiquitous molecule ethanol on model membranes in both the gel and fluid phases found by the structural and dynamical changes of the membrane in the publication "Partitioning of ethanol into lipid membranes and its effect on fluidity and permeability as seen by X-ray and neutron scattering".Cholesterol's effect on solid-supported, fluid, stacked lipid bilayers is described in Chapter 6 in the context of a binary lipid membrane.The structure of the domains found within the cholesterol/lipid membrane is informed by coarse-grained molecular dynamics simulations and neutron spectroscopy, which are in excellent agreement.The findings of the simulations and experiment are discussed in the publication "The Structure of Cholesterol in Lipid Rafts".Lastly, Chapter 7 will outline the main findings of these publications and an outlook will then be offered on the directions of future research given the advances made here and the climate of research in this field.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.005
Threshold uncertainty score0.015

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0010.001
Scholarly communication0.0010.001
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0050.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.011
GPT teacher head0.207
Teacher spread0.196 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2015
Admission routes1
Has abstractno

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Same venueScience and Technology Facilities CouncilSame topicLipid Membrane Structure and BehaviorFrench-language works237,207