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Record W7042888150

Pyrocarbon in shoulder hemi arthroplasty

2024· article· en· W7042888150 on OpenAlexaboutno aff

Bibliographic record

VenueOpen Archive (Karolinska Institutet) · 2024
Typearticle
Languageen
FieldMedicine
TopicShoulder Injury and Treatment
Canadian institutionsnot available
Fundersnot available
KeywordsArthroplastyOsteoarthritisShouldersImplantShoulder ProsthesisShoulder jointClinical trial
DOInot available

Abstract

fetched live from OpenAlex

Pyrolytic carbon, or pyrocarbon (PyC), has biocompatibility, a low friction coefficient and good wear resistance, making it a material of great potential for use in orthopaedics. PyC shoulder implants have shown promising mid-term results, but there is a shortage of research that support expectations of reduced glenoid wear in shoulder hemi arthroplasty (HA), and a lack of randomised trials comparing PyC to other options of shoulder arthroplasty. This thesis synthesizes findings from four studies focusing on shoulder arthroplasty outcomes and PyC, using data from the Swedish Shoulder Arthroplasty Registry (SSAR), and clinical trials. The studies investigate various implants and describe patient-reported outcome measures (PROMs), implant stability, and revision rates across different arthroplasty types. For study 1 we utilized data on 1140 shoulders from the SSAR to compare the results after resurfacing hemi arthroplasty (HA) and stemmed HA. Younger patients were shown to have higher revision rate irrespective of implant type. Patient-reported outcome was better for patients with primary osteoarthritis (OA) when compared to patients with secondary OA. In study 2 we evaluated the reliability, validity, and responsiveness of the Swedish translation of the Western Ontario Osteoarthritis of the Shoulder index (WOOS), affirming its suitability for assessing clinical outcomes in shoulder arthroplasty patients. We could also show that WOOS is a stable and consistent tool for longitudinal outcome measurement. Study 3 compares the performance of pyrocarbon (PyC) versus CobaltChromium (CoCr) resurfacing implants in a randomised controlled trial (RCT). Findings suggest that PyC implants may offer advantages in terms of reduced glenoid erosion and lower risk of revision compared to CoCr implants, although larger studies are needed to confirm these results. In study 4, extracting data from SSAR, we analysed results after stemmed PyC HA (n=101) and compared them to results after total shoulder arthroplasty (TSA) (n=142). We noted comparable hazard ratios (HR) for revision when adjusted for confounding factors. The results from PROMs for TSA were superior to PyC HA. In conclusion, PyC HA appears to be a safe alternative in shoulder arthroplasty surgery. Our results show comparable or better outcomes than other options for HA. In comparison to TSA, PyC HA have lower outcome in PROMs but similar risk of revision. The patient demographics differ between the groups, clouding interpretation of outcomes. List of scientific papers I. Ödquist M, Hallberg K, Rahme H, Salomonsson B, Rosso A. Lower age increases the risk of revision for stemmed and resurfacing shoulder hemi arthroplasty. Acta Orthop. 2018 Feb;89(1):3-9. https://doi.org/10.1080/17453674.2017.1411081 II. Hallberg K, Salomonsson B. Validity, reliability, and responsiveness of the Swedish version of Western Ontario Osteoarthritis of the Shoulder index. BMC Musculoskelet Disord. 2022 Apr 11;23(1):351. https://doi.org/10.1186/s12891-022-05300-1 III. Hallberg K, Stark A, Ross M, Salomonsson B, Sköldenberg O. A comparison of migration patterns, glenoid erosion and clinical outcomes between a metal and a pyrocarbon resurfacing shoulder arthroplasty. A prospective single-blind randomized trial using radiostereometric analysis. [Manuscript] IV. Hallberg K, Stark A, Salomonsson B, Sköldenberg O. Pyrocarbon Stemmed Hemi Arthroplasty compared to Anatomical Total Shoulder Arthroplasty. Short-to-Mid-term Outcomes from the Swedish Shoulder Arthroplasty Registry. [Manuscript]

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.002
Threshold uncertainty score0.007

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.001
Scholarly communication0.0010.000
Open science0.0000.000
Research integrity0.0010.000
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.034
GPT teacher head0.348
Teacher spread0.314 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2024
Admission routes1
Has abstractyes

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