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Record W7046037200

Deciphering the mechanisms involved in testicular gonocyte differentiation

2014· dissertation· en· W7046037200 on OpenAlexaff

Bibliographic record

VenueeScholarship@McGill (McGill) · 2014
Typedissertation
Languageen
FieldPhysics and Astronomy
TopicMagnetic confinement fusion research
Canadian institutionsMcGill University
Fundersnot available
KeywordsGonocyteSpermatogenesisGermlineGerm cellStem cellCellular differentiationRetinoic acidMeiosis
DOInot available

Abstract

fetched live from OpenAlex

A paired AR Androgen receptor A s A single ATP Adenosine triphosphate BAX BCL2-associated X protein BCE Belancanda chinensis extract BCL B-cell lymphoma BEP Bleomycin, etoposide, and cisplatin BLK B lymphoid tyrosine kinase BMP Bone morphogenic protein BPA Bisphenol A BRDU Bromodeoxyuridine BSA Bovine serum albumin BTB Blood testis barrier cAMP Cyclic adenosine monophosphate CCN Cyclin CD Cluster of differentiation CDH Cadherin cDNA Complementary deoxyribonucleic acid CIS Carcinoma in-situ CML Chronic myeloid leukemia CNTF Ciliary neurotrophic factor CPE Clostidium perfringens enterotoxin CRABP Cellular retinoic acid binding protein CRBP Cellular retinol binding protein C t Threshold cycle CUL Cullin CXCL Chemokine (C-X-C motif) ligand DAX Dosage-sensitive sex reversal, adrenal hypoplasia critical region, chromosome X DAZ Deleted in azoospermia DBD DNA binding domain DBP Di (n-butyl) phthalate DES Diethylstilbesterol DMEM Dulbecco's Modified Eagle's Medium DMSO Dimethyl sulfoxide DNA Deoxyribonucleic acid DNMT DNA (cytosine-5-)-methyltransferase DPC Days post coitum DPPA Dipeptide transporter DTT Dithiothreitol DUB Deubiquitinating enzyme E Embryonic day EC Embryonal carcinoma ECM Extra cellular matrix EGF Epidermal growth factor ER Estrogen receptor ERK Extracellular-signal-regulated kinase ESC Embryonic stem cell FBS Fetal bovine serum FBXO F-box protein FGF Fibroblast growth factor FGR Feline Gardner-Rasheed sarcoma viral oncogene FSH Follicle-stimulating hormone FTS Farnesylthiosalicylic acid GAPDH Glyceraldehyde 3-phosphate dehydrogenase GD Gestational day GDF Growth and differentiation factor GDNF Glial cell-derived neurotrophic factor GDNF family receptor alpha 1 GNRH Gonadotropin releasing hormone HCK Hemopoietic cell kinase hMSC Human bone marrow-derived mesenchymal stromal cell HRP Horseradish peroxidase HSP Heat shock protein ICC Immunocytochemistry ICSI Intracytoplasmic sperm injection IGF Insulin growth factor IgG Immunoglobulin G IHC Immunohistochemistry IN Intermediate IPA Ingenuity Pathway Analysis IVF In vitro fertilization JAK Janus kinase JAM Junctional adhesion molecule kDa Kilo-dalton KEGG Kyoto Encyclopedia of Genes and Genomes LBD Ligand binding domain LCK Lymphocyte-specific protein tyrosine kinase LH Luteinizing hormone LIF Leukemia inhibitory factor MEHP Mono-(2-ethylhexyl) phthalate MgCl Magnesium chloride MIN Minute MIS Mullerian inhibiting substance MMP Matrix metallopeptidase

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.003

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.013
GPT teacher head0.239
Teacher spread0.226 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2014
Admission routes1
Has abstractyes

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