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Record W7046096147

Caractérisation de la fonction NA+/K+- atpasique branchiale chez des ombles de fontaine (Salvelinus fontinalis) anadromes et résidents de la rivière Laval

2014· other· fr· W7046096147 on OpenAlexaboutno aff

Bibliographic record

VenueSémaphore (Université du Québec à Rimouski) · 2014
Typeother
Languagefr
FieldPhysics and Astronomy
TopicAstronomy and Astrophysical Research
Canadian institutionsnot available
Fundersnot available
KeywordsBioeconomicsZea maysCitrus fruit
DOInot available

Abstract

fetched live from OpenAlex

RÉSUMÉ : Les ombles de fontaine (Salvelinus fontinalis) anadromes et résidents de la rivière Laval (Côte-Nord, Québec) représentent deux populations génétiquement et physiologiquement distinctes vivant en sympatrie. L'anadromie implique un défi osmorégulatoire pour les poissons, entraînant plusieurs ajustements physiologiques, incluant l'augmentation de l'activité de la Na+/K+-ATPase branchiale. Cette dernière est considérée comme critique lors de l'acclimatation en eau salée chez les salmonidés. La présence de deux isoformes (ala et alb) de la sous-unité catalytique de la Na+/K+-ATPase branchiale, différemment exprimés en fonction de la salinité a récemment été démontrée chez d'autres espèces de salmonidés anadromes. Afin de vérifier s'il existe des différences de capacité osmorégulatoire en eau salée au niveau de la Na+/K+-ATPase branchiale entre les deux formes, des ombles de fontaine anadromes et résidents de la rivière Laval (l+) ont été graduellement transférés dans des eaux estuariennes de juin à août (augmentation de 2% par jour, salinité finale 28%) et comparés à un groupe contrôle demeuré en eau douce. Avant le transfert et 3, 7, 14 et 60 jours après le transfert en eau salée, des mesures d'activités enzymatiques absolue et spécifique de la Na+/K+-ATPase branchiale ont été réalisées. Les expressions relatives des deux isoformes ala et alb ont été mesurées à l'aide d'analyses PCR quantitatives en temps réel. Les résultats démontrent des réponses enzymatique et d'expression génique Na+/K+-ATPasique branchiales similaires chez les deux formes; soit une augmentation des activités spécifique et absolue après 14 jours (28%), ainsi qu'une diminution de l'expression de l'isoforme alb après 14 jours (28%) et une augmentation de l'expression de l'isoforme alb après 60 jours (28%). Ces résultats suggèrent la conservation chez les résidents de la rivière Laval d'une certaine capacité d'habileté hypo-osmorégulatoire en eau salée au niveau de cette enzyme. L'expression différentielle des deux isoformes en fonction de la salinité suggère une activité ou une régulation de transport différente reliée à l'absorption ou l'excrétion d'ions. Un décalage entre les réponses d'expression génique et d'activité enzymatique a été observé, traduisant peut-être des inhibitions de la traduction ou simplement des temps de réponses différents pour ces deux processus. -- Mots clés : Omble de fontaine, Na+/K+-ATPase branchiale, anadromie, acclimatation eau salée, régulation ionique. -- ABSTRACT : Anadromous and river-resident brook charr (Salvelinus fontinalis) from Laval river (Northern shore, Québec) representent two genetically and physiologically distinct populations, living in sympatry. Anadromy implies an osmoregulatory challenge for fish and several physiological adjustments must be set up, including the up regulation of gill Na+/K+-ATPase activity, considered as a critical physiological variable for successful seawater acclimation in salmonids. It has been recently demonstrated in other anadromous salmon id species, that the two isoforms (ala and alb) of this enzyme are differently expressed according to salinity. In order to verify if there are differences in the saItwater osmoregulatory capacity at the gill Na+/K+-ATPase level in both forms, anadromous and river-resident brook charr (1+) were gradually transferred in estuarine water from June to August (increase of 2% day-1, final 28%) and compared to a control group stayed in fresh water. Before the transfer and after 3, 7, 14 and 60 days following saltwater transfer, enzymatic gill Na+/K+-ATPase absolute and specifie activities were measured. Relative expression of the two isoforms ala and alb were analysed using quantitative real time PCR. The results showed similar gill Na+/K+-ATPase responses at enzymatic and genomic expression levels in both forms of brook charr: up regulation of absolute and specifie activity after 14 days (28%), down regulation of ala isoform after 14 days (28%) and up regulation of alb isoform after 60 days (28%). These results suggest a certain conservation of the hypo-osmoregulatory capacity in river-resident charr from Laval river at the gill Na+/K+-ATPase level. The differential expression of these isoforms according to salinity suggest that ala and alb may differ in transport activity or regulation related to ion uptake and secretion, respectively. A time lapse between enzymatic and genomic expression responses has been observed and may indicate translation inhibition or different time response of these two mechanisms. -- Keywords : Brook charr, gill Na+/K+-ATPase, anadromy, seawater acclimation, ion regulation.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.907
Threshold uncertainty score0.184

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0010.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.004
GPT teacher head0.221
Teacher spread0.217 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2014
Admission routes1
Has abstractyes

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