Structural analyses of the putative mannosylphosphate transferase, Ktr6p from «Saccharomyces cerevisiae»
Bibliographic record
Abstract
The post-translational addition of sugar moieties onto proteins plays an important role in protein folding, secretion, signaling, and is even thought to partake in cell-cell adhesion. In eukaryotes, the biosynthesis of N-glycans begins with the transfer of Glc3Man9GlcNAc2 to the amide group of an asparagine situated in the tripeptide Asn-X-Thr(Ser), of a protein. Subsequent removal of three glucoses and one mannose occurs in the Endoplasmic Reticulum. In yeast, those proteins that require further maturation, e.g. those destined to enter the secretory pathway, are sent to the cis-Golgi. The core, Man8GlcNAc2, is then decorated with additional mannoses and mannose-1-phosphates.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.002 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".