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Record W7053070076

Studying Past Ecosystems and Human Behaviors Using Environmental and Ancient DNA

2021· other· en· W7053070076 on OpenAlexaboutno aff

Bibliographic record

VenueeScholarship (California Digital Library) · 2021
Typeother
Languageen
FieldEngineering
TopicParticle Accelerators and Free-Electron Lasers
Canadian institutionsnot available
Fundersnot available
KeywordsNucleofectionExclosurePopulationProteogenomicsTSG101Limiting
DOInot available

Abstract

fetched live from OpenAlex

Isolating and studying degraded DNA from preserved organismal remains and environmental samples allows new inferences about past ecosystem compositions, population dynamics, and, in the context of archaeological remains, human interactions with their environment. In this dissertation, I addressed how sequencing depth and stochasticity of metabarcoding PCR influences various measures of biodiversity. I found that sequencing depth and stochasticity between PCR replicates significantly influence estimates of alpha but not beta diversity. In my second chapter, I used eDNA isolated from permafrost cores spanning the last 50,000 years in the Klondike, Canada to characterize community composition and turnover of plant and mammalian communities. In this chapter, I characterized floral and faunal change over the last 50,000 years, with clear shifts from steppe to boreal forest habitat delineated with the presence and absence of arctic ground squirrels and woody plants. Finally, I isolated ancient DNA from archaeological moccasins to observe hunting patterns of Bison used by occupants of the Promontory Caves of Utah, an archaeological site occupied 1240-1290 AD. I found the majority (87%) of moccasins were constructed from female bison, supporting prior hypotheses of hunting strategies targeting cow-calf herds at the end of fall preparing for overwintering. My dissertation highlights some of the many questions that degraded DNA present in soil, bone, and preserved hides can contribute towards answering.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.017
Threshold uncertainty score0.033

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.002
Science and technology studies0.0010.001
Scholarly communication0.0010.001
Open science0.0000.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.014
GPT teacher head0.203
Teacher spread0.189 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2021
Admission routes1
Has abstractyes

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