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Record W7055397081

Characterization of Breast Cancer with Manganese-enhanced Magnetic Resonance Imaging

2014· dissertation· en· W7055397081 on OpenAlexvenueno aff

Bibliographic record

VenueLibrary and Archives Canada (Government of Canada) · 2014
Typedissertation
Languageen
FieldEngineering
TopicParticle accelerators and beam dynamics
Canadian institutionsnot available
Fundersnot available
KeywordsBreast cancerMagnetic resonance imagingCancerCancer cellMetastatic breast cancerHuman breastCancer imagingMedical imagingCharacterization (materials science)
DOInot available

Abstract

fetched live from OpenAlex

Highly metastatic cancer cells are more likely to escape and form metastases,\nand only minimal improvements in treatment can be achieved. Despite metas-\ntases being the primary cause of cancer-related mortality, they often proceed\nunnoticed. Current imaging modalities rely solely on the morphological fea-\ntures of the tumor for characterization, rather than cellular differences. Our\ngoal is to develop an MR cellular imaging capability for characterizing the po-\ntential of breast cancer cells to metastasize and enable early cancer detection\nusing manganese. Experiments on breast cell lines demonstrated that aggres-\nsive cancer cells significantly enhanced on T1 -weighted MR images as a result\nof a higher uptake and retention of manganese. These results suggest that dif-\nferences in uptake of manganese can help the detection and characterization\nof breast cancers. The proposed technique can also be useful for other cancers,\nand could bring a critically needed dimension to cancer imaging.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.509
Threshold uncertainty score0.980

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.001
GPT teacher head0.133
Teacher spread0.132 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2014
Admission routes1
Has abstractyes

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