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Record W7062358473

Towards Automated Clinical Diagnostic Decision Support using Machine Learning

2022· dissertation· en· W7062358473 on OpenAlexfundno aff

Bibliographic record

VenuemediaTUM (Technical University of Munich) · 2022
Typedissertation
Languageen
FieldEngineering
TopicAdvanced Power Generation Technologies
Canadian institutionsnot available
FundersCanadian Institutes of Health ResearchNational Institutes of HealthGenentechIXICOH. Lundbeck A/SDeutschen Schwindel- und GleichgewichtszentrumServierPfizerNovartis Pharmaceuticals CorporationEisaiU.S. Department of DefenseMeso Scale DiagnosticsBundesministerium für Bildung und ForschungBiogenBristol-Myers SquibbEli Lilly and CompanyBioClinicaAlzheimer's Drug Discovery Foundation
KeywordsDecision support systemClinical decision support systemClinical PracticeTraining setClinical decision makingSupport vector machine
DOInot available

Abstract

fetched live from OpenAlex

Applications for clinical diagnostic decision support have received a lot of attention recently and research works are ongoing. Despite recent successes, there are still open challenges that remain. In this work, we address the challenge of incomplete information in clinical data, the notion of cost-aware and peri-diagnostic support, and the translation of these approaches to the clinical research setting.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.005
metaresearch head score (Gemma)0.020
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: none
GenreCandidate signal: Methods · Consensus signal: Methods
Teacher disagreement score0.005
Threshold uncertainty score0.029

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0050.020
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0020.002
Science and technology studies0.0010.001
Scholarly communication0.0040.002
Open science0.0010.003
Research integrity0.0020.004
Insufficient payload (model declined to judge)0.0030.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.015
GPT teacher head0.283
Teacher spread0.268 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2022
Admission routes1
Has abstractyes

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