Chronic Wasting Disease: Crossing the Species Barrier into Human Populations
Bibliographic record
Abstract
Chronic Wasting Disease (CWD) is a prion disease causing degeneration of the centralnervous system within various species of deer, elk, moose and caribou, collectively known as cervids. CWD originated in Colorado in the 1960s and has spread to 29 states, four Canadian provinces, three Scandinavian countries and South Korea. Prions are excreted through bodily fluids, waste, and decomposing carcasses that remain inthe environment, posing a potential threat to other species. A significant number of people are directly exposed to CWD prions through handling and consumption of contaminated cervid carcasses and using cervid brains for tanning. Similar exposure, through incorporation of sheep prions into the food chain, has resulted in a prion disease called Bovine Spongiform Encephalopathy (Mad Cow Disease) and subsequent transmission of cow prions to humans, resulting in variant Creutzfeldt-Jakob Disease. This study aims to address the risks of CWD transmission to humans and cervids globally.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.001 | 0.001 |
| Scholarly communication | 0.001 | 0.001 |
| Open science | 0.000 | 0.001 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.005 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".