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Record W7065987340

Evaluation of the Long-term Cardiac Prognosis of Kawasaki Disease in Canada

2022· dissertation· en· W7065987340 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

aboutThe title or abstract carries a Canadian signal from the geographic lexicon.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

VenueTSpace (University of Toronto) · 2022
Typedissertation
Languageen
FieldPhysics and Astronomy
TopicElectrical and Electromagnetic Research
Canadian institutionsnot available
Fundersnot available
KeywordsMaceKawasaki diseaseIncidence (geometry)CohortPopulationCardiovascular eventRelative riskHazard ratio
DOInot available

Abstract

fetched live from OpenAlex

To evaluate the long-term risk of hypertension and other major adverse cardiac events (MACE) in individuals with Kawasaki Disease (KD), an inception cohort of 1,169 KD patients diagnosed between 1991-2008 was linked with health administrative data and their risk was compared with 11,690 population comparators. During 21,792 and 218,578 patient years (PY) of follow-up among KD and comparators, respectively, incidence rates of hypertension were 1.38 (95%CI 0.93-1.97) vs 0.62 (95%CI 0.52-0.74)/1000 PY. Multivariable cause-specific hazard models estimated that KD patients had an increased risk for hypertension and MACE. This increased risk for hypertension and MACE was also observed in KD patients with normal coronary arteries relative to comparators. MACE risk was higher in KD patients with coronary aneurysms. For all cardiac outcomes, the increased risk was highest following diagnosis and diminished over follow-up. Despite the relative increase, the low event rates suggest that cardiac prognosis in KD remains favorable.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.266
Threshold uncertainty score0.990

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0110.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.012
GPT teacher head0.264
Teacher spread0.251 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it