Infección por Clostridium difficile en Medicina Interna
Bibliographic record
Abstract
Clostridium difficile fue descrito inicialmente como un componente de la flora intestinal normal de los neonatos. Sin embargo, no fue hasta 1978 cuando se le identificó como una importante causa de colitis pseudomembranosa asociada al uso de clindamicina. Este agente es responsable de un espectro de enfermedades denominado infección por C. difficile (ICD), que va desde un cuadro de diarrea no complicada y colitis pseudomembranosa hasta el megacolon tóxico y, en ocasiones, sepsis e incluso muerte. Aunque la ICD está asociada sobre todo al uso de los antibióticos, su epidemiología ha cambiado en las tres últimas décadas. Durante los años 2002 a 2005 se identificó en la provincia de Quebec (Canadá) una epidemia de ICD causada por la cepa BI/NAP1/027. Desde entonces en numerosos países se han comunicado brotes regionales de ICD, de colitis grave e incluso de muerte, causados por esta cepa. Además, estas infecciones se están empezando a identificar en poblaciones previamente no consideradas en riesgo, tales como sujetos sin contacto reciente con el sistema de atención sanitaria, embarazadas, niños, y pacientes con enfermedad inflamatoria intestinal.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.004 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.003 | 0.004 |
| Science and technology studies | 0.001 | 0.001 |
| Scholarly communication | 0.002 | 0.001 |
| Open science | 0.001 | 0.001 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.007 | 0.002 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".