Early life influences on adult sleep and health risk indicators : examining mediational relationships
Bibliographic record
Abstract
Evidence suggests that early life stress increases risk for cardiovascular disease in adulthood. However, less is known about how early life experiences propagate risk into adulthood. The current study examines a potentially critical mediator of the relationship between early life stress and disease outcomes, namely poor sleep. Early life stress was hypothesized to contribute to poor sleep, as well as to other physiological health risk indicators (i.e., BP and BMI), by affecting adult psychosocial functioning. Further, poor sleep was examined as a mediator between adult psychosocial functioning and BP and BMI. An online sample and a university population sample completed measures of early life stress (i.e., a measure of childhood socioeconomic status and the risky family questionnaire), along with measures of adult psychosocial functioning and sleep quality. The university sample also participated in a 6-night actigraphy assessment to obtain objective sleep measurements. Results indicated that adult psychosocial functioning mediated the relationship between family risk in childhood and poorer subjective sleep quality for both sample populations. However, in the university sample, family risk also demonstrated a direct effect with respect to poorer subjective sleep quality, as well with respect to a latent factor reflecting physical restlessness and wakefulness during the sleep period. Family risk also demonstrated an indirect relationship with sleep length, largely via relationships with social support. Results did not suggest that family risk was associated with adult BP or BMI. However, in the university sample, social support, perceived stress, and negative affect were found to be significant predictors of BMI, and social support was found to be predictive of BP indices. Hypotheses examining sleep as a mediator of the relationship between psychosocial variables and BP and BMI were not well supported. Overall, results suggest that an adverse early childhood environment is a potentially important determinant of adult psychosocial and sleep functioning, which in turn may increase disease risk.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.002 | 0.009 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.001 | 0.001 |
| Open science | 0.001 | 0.001 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.003 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".