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Record W7081988217 · doi:10.1016/j.ynirp.2025.100284

Building blocks of functional connectivity measures for aperiodic electrophysiological brain signals

2025· article· en· W7081988217 on OpenAlexaff

Bibliographic record

VenueNeuroimage Reports · 2025
Typearticle
Languageen
FieldEngineering
TopicGeodetic Measurements and Engineering Structures
Canadian institutionsUniversité Laval
FundersNederlandse Organisatie voor Wetenschappelijk Onderzoek
KeywordsAperiodic graphSpurious relationshipInvariant (physics)ElectroencephalographyPermutation (music)Measure (data warehouse)Functional connectivityMacaque

Abstract

fetched live from OpenAlex

A challenge in interpreting functional connectivity results in electroencephalography (EEG) data is volume conduction. A common way to mitigate spurious connectivity due to volume conduction is to use connectivity measures that are insensitive to volume conduction. Examples of such measures are the imaginary coherence, the lagged coherence, and the (weighted) phase-lag index. Their insensitivity to volume conduction stems from an invariant property and it is of both practical and theoretical interest to identify all measures with this property. In this study we derive a set of invariant connectivity measures that are fundamental in the sense that all others can be constructed from them by combination. These ”building blocks” of connectivity measures quantify the lack of invariance of multivariate EEG signals under permutation of the time-points. We use this result to construct a new connectivity measure for stationary aperiodic EEG signals, referred to as the temporal irreversibility index (TII) and illustrate its use by applying it to local field potentials recorded from primary visual cortex of a macaque monkey and to EEG data from comatose survivors of cardiac arrest. As far as we are aware, the TII is currently the only functional connectivity measure for aperiodic signals that is insensitive to volume conduction.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.010
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.004
Threshold uncertainty score0.009

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.010
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0040.002
Science and technology studies0.0000.002
Scholarly communication0.0010.002
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.017
GPT teacher head0.238
Teacher spread0.221 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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