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Record W7084627432

Management and Treatment of Benign Prostatic Hyperplasia Symptoms: Current Insights

2025· article· en· W7084627432 on OpenAlexaboutno aff

Bibliographic record

VenueDOAJ (DOAJ: Directory of Open Access Journals) · 2025
Typearticle
Languageen
FieldDecision Sciences
TopicConstruction Project Management and Performance
Canadian institutionsnot available
Fundersnot available
KeywordsLower urinary tract symptomsHyperplasiaBenign prostatic hyperplasia (BPH)Quality of life (healthcare)ProstateProstate diseasePatient careUrinary systemQuality management
DOInot available

Abstract

fetched live from OpenAlex

Othmane Zekraoui,1 Naeem Bhojani,1,2 Kevin C Zorn,3 Dean Elterman,4 Bilal Chughtai5,6 1Faculty of Medicine, Université de Montréal, Montreal, QC, Canada; 2Division of Urology, Department of Surgery, Université de Montréal Health Center, Montreal, QC, Canada; 3BPH Canada Prostate Surgical Institute, Mont-Royal Surgical Center, Montreal, QC, Canada; 4Division of Urology, Department of Surgery, University of Toronto, Toronto, ON, Canada; 5Department of Urology, Northwell Health, Plainview, NY, USA; 6Department of Urology, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell Health, Hempstead, NY, USACorrespondence: Bilal Chughtai, Northwell Health, 8 Greenfield Road, Syosset, NY, 11791, USA, Email Bchughtai@northwell.eduAbstract: Benign prostatic hyperplasia (BPH) is a common cause of lower urinary tract symptoms (LUTS) in aging men that can significantly impair their quality of life. This review provides updated insights into this condition’s pathophysiology, diagnostic strategies, and the full spectrum of management approaches, including lifestyle changes, medical management, minimally invasive surgical therapies, and traditional surgical interventions. For each modality, we sought to provide an overview of the mechanism of action, efficacy, safety, as well as guideline-backed patient selection recommendations issued by three major BPH guidelines. With the various existing management strategies, the role of shared decision making is emphasized to align the therapeutic choices with symptom severity, prostate anatomy, comorbidities, but also with individual patient values. By summarizing the current and most updated literature on BPH management and treatment, our goal is to support evidence-based clinical decisions and improve care and outcomes for men suffering from BPH-related LUTS.Keywords: prostatic hyperplasia, lower urinary tract symptoms, male, quality of life

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesScholarly communication, Insufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.589
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0020.002
Science and technology studies0.0000.000
Scholarly communication0.0010.002
Open science0.0020.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.304
GPT teacher head0.587
Teacher spread0.283 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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