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Regulation of Glucose Transporters by Insulin and Exercise: Cellular Effects and Implications for Diabetes

2001· article· en· W7093320467 on OpenAlexaff

Bibliographic record

VenueComprehensive physiology · 2001
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicMetabolism, Diabetes, and Cancer
Canadian institutionsUniversité LavalHospital for Sick Children
Fundersnot available
KeywordsGlucose transporterTransporterDiabetes mellitusInsulinChromosomal translocationGlucose uptakeCarbohydrate metabolismGLUT4

Abstract

fetched live from OpenAlex

Abstract The sections in this article are: Properties of the Glucose Transporter Families The GLUT Family Acute Regulation of Glucose Transporters by Insulin‐Responsive Tissues The Glucose Transporter Recruitment Hypothesis Insulin‐Responsive Glucose Transporters Testing and Verification of the Recruitment Hypothesis Biochemical Characteristics of The Glut‐4‐Containing Organelle Resident Proteins Proteins Involved in Vesicle Docking and Fusion Low‐Molecular‐Weight G Proteins Insulin Signals Involved in The Mobilization of Glucose Transporters Testing the Participation of a Signaling Pathway Effects of Prolonged Exposure to Insulin on the Glucose Transporters Regulation of Glucose Transporters by Exercise Effects of Exercise In Vivo: Roles of Hypoxia, Blood Flow, and Muscle Fiber Composition Glucose Transporters in Exercised Muscles Signaling Mechanism of Contraction‐Induced Glucose Transport Glucose Transporters in Diabetes Glucose Transporters in Insulin‐Dependent Diabetes Mellitus Glucose Transporters in Obesity and Non‐Insulin‐Dependent Diabetes Mellitus Proposed Mechanisms Leading to Impaired GLUT‐4 Translocation in Diabetes GLUT‐4 Translocation Defect: Primary or Acquired? Effects of Antidiabetic Drugs on Glucose Transporters Lessons from the Manipulation of Glucose‐Transporter Expression by Transgenic Mouse Approaches and Natural Mutations GLUT‐1 Overexpression in Muscle GLUT‐4 Overexpression in Tissues of Natural Expression Selective Overexpression of GLUT‐4 in Muscle GLUT‐4 Overexpression in Fat GLUT‐4 Ablation A Naturally Occurring Genetic Abnormality in GLUT‐1 Expression Concluding Remarks

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.214
Threshold uncertainty score0.475

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.008
GPT teacher head0.233
Teacher spread0.225 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2001
Admission routes1
Has abstractyes

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