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Record W7093330139 · doi:10.63209/2025.1583

Sélection et utilisation écoresponsables des médicaments en inhalation à l’Institut universitaire de cardiologie et de pneumologie de Québec–Université Laval

2025· article· W7093330139 on OpenAlexaffabout

Bibliographic record

VenuePharmactuel · 2025
Typearticle
Language
FieldMedicine
TopicInhalation and Respiratory Drug Delivery
Canadian institutionsInstitut universitaire de cardiologie et de pneumologie de Québec
Fundersnot available
KeywordsInhalationMultimeterOccupational exposure

Abstract

fetched live from OpenAlex

Objectif : Faire une sélection et une utilisation écoresponsables des médicaments en inhalation, notamment par la réduction des aérosols-doseurs puisqu’ils sont des émetteurs importants de gaz à effet de serre. Méthode : Un groupe de travail multidisciplinaire a été créé pour réévaluer la liste des médicaments administrés par inhalation sur le formulaire de l’Institut et leur utilisation. Parallèlement, la pharmacie a mené un projet de gestion écoresponsable du circuit du médicament. Les employés de la pharmacie ont reçu un sondage à remplir, et certains ont participé à un groupe de discussion. Un plan d’action a ensuite été préparé. Résultats : Une procédure a été élaborée pour réutiliser les aérosols-doseurs contenant un bronchodilatateur en physiologie respiratoire. Des chambres d’espacement réutilisables après stérilisation ont été achetées ainsi que des boîtes pour le recyclage des aérosols-doseurs. Une révision complète des médicaments en inhalation figurant sur le formulaire de l’Institut a été effectuée afin de privilégier les dispositifs à poudre sèche lorsque c’est possible. Conséquemment, la mise à jour du tableau de substitution automatique vers ces dispositifs a été entériné par le Comité de pharmacologie. Les dispositifs d’inhalation que les patients apportent de leur domicile sont employés, avec leur consentement, pendant leur séjour à l’urgence. Un plan de communication a été établi. Conclusion : Les aérosols-doseurs sont parmi les médicaments qui émettent le plus de gaz à effet de serre. Les actions qui émanent de ce projet ont réduit de façon substantielle les émissions des gaz à effet de serre et ont entraîné des économies importantes. Abstract Objective: To perform an eco-responsible selection and use of inhalers, particularly by reducing the use of metered-dose inhalers (MDIs), which are significant emitters of greenhouse gases. Method: A multidisciplinary working group was created to reassess the inhaled medications list on the Institute’s formulary and their use. Simultaneously, the pharmacy launched a project for the eco-responsible management of the medication circuit. Pharmacy staff received a survey to fill, and some participated in a focus group. An action plan was then prepared. Results: A procedure was established to reuse MDIs containing a bronchodilator in the respiratory physiology department. Reusable spacer chambers that can be sterilized were purchased, along with boxes for recycling MDIs. A comprehensive review of inhalation medications on the Institute’s formulary was conducted to prioritize dry powder inhalers whenever possible. Consequently, the automatic substitution chart was updated to reflect this preference and approved by the Pharmacy and Therapeutic Committee. Inhalation devices brought by patients from home are used, with their consent, during their stay in the emergency department. A communication plan was also developed. Conclusion: MDIs are among the medications with the highest greenhouse gas emissions. The actions resulting from this project have significantly reduced greenhouse gas emissions and led to substantial cost savings.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.121
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0010.000
Scholarly communication0.0000.001
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.033
GPT teacher head0.343
Teacher spread0.310 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes2
Has abstractyes

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