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Record W7095138137

Commentary CMAJ

2016· article· en· W7095138137 on OpenAlexaboutno aff

Bibliographic record

Venuenot available
Typearticle
Languageen
FieldMedicine
TopicPrenatal Screening and Diagnostics
Canadian institutionsnot available
Fundersnot available
KeywordsVareniclineScrutinyHarmDrug trialAdverse effectAlternative medicine
DOInot available

Abstract

fetched live from OpenAlex

All editorial matter in CMAJ represents the opinions of the authors and not necessarily those of the Can adian Medical Association. 1346 CMAJ, September 6, 2011, 183(12) © 2011 Canadian Medical Association or its licensors In this issue of CMAJ, Singh and colleagues1present a meta-analysis assessing the risk ofserious adverse cardiovascular events asso-ciated with the use of varenicline for smoking cessation. The paper raises additional questions about a drug that has already come under scrutiny by the US Food and Drug Administra-tion for neuropsychiatric safety concerns,2 and within the past month, the drug has been the focus of another warning regarding an association between it and serious adverse cardiovascular events.3 This new warning is based on observa-tions published in a randomized trial of vareni-cline for the treatment of tobacco dependence among participants with known cardiovascular

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.006
metaresearch head score (Gemma)0.060
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Commentary · Consensus signal: Commentary
Teacher disagreement score0.931
Threshold uncertainty score0.230

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0060.060
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.002
Bibliometrics0.0020.002
Science and technology studies0.0030.002
Scholarly communication0.0040.004
Open science0.0040.002
Research integrity0.0280.029
Insufficient payload (model declined to judge)0.0690.035

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.018
GPT teacher head0.271
Teacher spread0.253 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designNot applicable
Domainnot available
GenreCommentary

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2016
Admission routes1
Has abstractyes

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