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Record W7095746117

clinical challenge ❖ défi clinique MOTHERISK UPDATE Ever y year, the Centre forInfectious Disease Prevention

2000· article· en· W7095746117 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

aboutThe title or abstract carries a Canadian signal from the geographic lexicon.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

Venuenot available
Typearticle
Languageen
FieldBusiness, Management and Accounting
TopicManagement Theory and Practice
Canadian institutionsnot available
Fundersnot available
KeywordsZidovudinePregnancyTransmission (telecommunications)Human immunodeficiency virus (HIV)GestationPrenatal careSidaClinical research
DOInot available

Abstract

fetched live from OpenAlex

there were 1111 positive HIV test reports in Canada; 204 concerned adult women.2 One third of these women contracted the primary infec-tion through heterosexual exposure.3 In the past, many HIV-infected pregnant women were unaware of their HIV status, and their infection was undetected until either they or their children devel-oped symptoms. It is cur-rently recommended that all pregnant women be offered an HIV screening test as part of their prenatal care. The HIV test is performed only after counseling and obtaining informed consent.4 Human immunodeficiency virus can be transmitted from mother to child during gestation and delivery or through breast milk. The rate of transmission of HIV from mother to child during pregnancy without inter vention ranges between 15% and 40%; the rate with optimal ARV management is 1 % to 3%.5 Testing for HIV during pregnancy provides an important opportunity for starting ARV treatment if necessary. Therapy for the mother reduces the risk of HIV transmission to her child. While zidovudine monotherapy was initially the most frequently prescribed regimen, combination therapy is now more common. Combinations are either two nucleo-side reverse transcriptase inhibitors (NRTIs), such as zidovudine and lamivudine, or two NRTIs with a protease inhibitor. In Canada, the cur-rently licensed ARV agents are the NR TIs abacavir, didanosine, lamivudine, stavudine, zalcitabine, and zidovudine; the non-nucleo-side reverse transcriptase Do you have questions about the safety of drugs, chemicals,radiation, or infections in women who are pregnant or

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesInsufficient payload (model declined to judge)
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.849
Threshold uncertainty score0.994

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.001
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0350.007

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.028
GPT teacher head0.301
Teacher spread0.274 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Quick stats

Citations0
Published2000
Admission routes1
Has abstractyes

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