and 4Anesthesia, University Health Network (Toronto General Hospital, Toronto Western Hospital, and Princess Margaret Hospital),
Bibliographic record
Abstract
A multicenter prospective, randomized, controlled trial, with 0.5 % tincture of chlorhexidene versus 10 % povidone-iodine as cutaneous antisepsis for central venous catheter (CVC) inser-tion, was conducted for patients in intensive care units. Of 374 patients, 242 had a CVC inserted for 13 days and were used for the primary analysis. Outcomes included catheter-related bacteremia, signi®cant catheter colonization (>15 colony-forming units [cfu]), exit-site infection, serial quantitative exit-site culture (every 72 h), and molecular subtyping of all isolates. Patients in both study groups were comparable with respect to age, sex, underlying disease, length of hospitalization, reason for line insertion, and baseline APACHE II score. Documented catheter-related bacteremia rates were 4.6 cases per 1000 catheter-days in the chlorhexidine group ( ) and 4.1 cases per 1000 catheter-days in the povidone-iodinen p 125 group ( ; not signi®cant [NS]). Signi®cant catheter-tip colonization occurred in 24 (27%)n p 117 of 88 patients in the povidone-iodine group and in 31 (34%) of 92 patients in the chlorhexidine group (NS). A mean exit-site colony count of cfu/mL per 25 cm2 of the surface area55.9 3 10 of skin in the povidone-iodine group versus cfu/mL per 25 cm2 in the chlorhexidine53.1 3 10 group (NS) was found. There was a trend toward fewer exit-site infections in the chlorhexidine
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.001 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.001 | 0.001 |
| Scholarly communication | 0.001 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.014 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".