RESEARCH Distinct roles of KAP1, HP1 s
Bibliographic record
Abstract
and/or in specific tissues. A number of ERV1Z3, Canada Full list of author information is available at the end of the articleBackground Endogenous retrovirus-like sequences (ERVs) are fossils of ancient retroviral integrations into the mammalian germline. Multiple independent colonization events have led to the accumulation of over 400 different ERV families with defined transcriptional patterns, often limited to spe-cific developmental stages and cell types. Based on the similarity of their reverse transcriptase genes, ERVs are grouped into three classes: I, II and III, most closely re-lated to exogenous gammaretroviruses, betaretroviruses and spumaretroviruses, respectively [1]. Most ERVs in each class are no longer capable of transcription and/or retrotransposition due to the accumulation of mutations and/or efficient targeting by host silencing mechanisms that act at various stages of the viral life cycle [2]. Never-theless, many ERVs possess functional regulatory se-quences that direct transcription at specific developmental
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.000 |
| Science and technology studies | 0.001 | 0.001 |
| Scholarly communication | 0.001 | 0.001 |
| Open science | 0.001 | 0.001 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.010 | 0.004 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".