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Record W7097049759

Research

2015· article· en· W7097049759 on OpenAlexaboutno aff

Bibliographic record

Venuenot available
Typearticle
Languageen
FieldMedicine
TopicHepatitis C virus research
Canadian institutionsnot available
Fundersnot available
KeywordsSerostatusHepatitis C virusHepatitis CDiseaseHuman immunodeficiency virus (HIV)PopulationCause of deathIntravenous drug
DOInot available

Abstract

fetched live from OpenAlex

Seropositivity for hepatitis C virus (HCV) is prevalentamong people who are HIV-positive.1 Although sev-eral authors have found that liver disease has become a leading cause of death among those infected with HIV,2–4 debate continues as to the effect of HCV infection on HIV disease progression, as measured by new AIDS-defining ill-nesses, CD4 T-cell decline or HIV-related mortality.4–9 Mortality in this population can be strongly confounded by factors such as adherence to a course of antiretroviral ther-apy (ART), illicit use of injected drugs and previous admin-istration of ART. During the 1990s, Vancouver experienced an explosive epidemic of HIV and HCV infection among the city’s 10 000 users of injected drugs;10 currently, more than 30% are coinfected with both viruses.11 Here we report on the effect of HCV serostatus on the risk of death among par-ticipants in a population-based HIV and AIDS treatment program who had received no previous ART, adjusting for adherence to ART and history of injection drug use. Speci-fically, we describe the effect of HCV serostatus on risk of death, particularly HIV-related death.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.005
metaresearch head score (Gemma)0.015
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Other · Consensus signal: Other
Teacher disagreement score0.695
Threshold uncertainty score0.000

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0050.015
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0020.003
Science and technology studies0.0030.001
Scholarly communication0.0050.003
Open science0.0020.002
Research integrity0.0020.002
Insufficient payload (model declined to judge)0.3050.148

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.609
GPT teacher head0.580
Teacher spread0.029 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designNot applicable
Domainnot available
GenreOther

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2015
Admission routes1
Has abstractyes

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