PII S0960-9822(02)01355-6 A Formin Homology Protein and a Profilin Are Required for Cytokinesis and Arp2/3-Independent Assembly of Cortical Microfilaments in C. elegans
Bibliographic record
Abstract
2Institute of Molecular Biology and Biochemistry uncapping or severing or when microfilaments are nucleated de novo [3]. The Arp2/3 complex, an assemblage of two actin-related proteins (Arp2 and Arp3) and five additional proteins (ArpC1–ArpC5), is one important nucleator of MFs. However, it remains unknown whether the Arp2/3 complex is generally required for MF assem-Simon Fraser University bly during development, or if multiple proteins or protein Burnaby, British Columbia V5A 1S6 complexes each nucleate specific subsets of MFs. Canada Profilin was initially identified as an actin-sequestering protein that binds to G-actin with 1:1 stoichiometry [4, 5]. However, profilin can also stimulate MF polymeriza-Summary
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.001 | 0.000 |
| Science and technology studies | 0.001 | 0.001 |
| Scholarly communication | 0.001 | 0.001 |
| Open science | 0.001 | 0.001 |
| Research integrity | 0.002 | 0.001 |
| Insufficient payload (model declined to judge) | 0.782 | 0.720 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".