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Record W7100365573

Research letter Failure to prevent perinatal HIV infection

2014· article· en· W7100365573 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

aboutThe title or abstract carries a Canadian signal from the geographic lexicon.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

Venuenot available
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicDNA and Biological Computing
Canadian institutionsnot available
Fundersnot available
KeywordsPregnancyHuman immunodeficiency virus (HIV)Sick childTransmission (telecommunications)Prenatal careSida
DOInot available

Abstract

fetched live from OpenAlex

Perinatally transmitted HIV infections have continued to occur in Ontario despite the introduction of universal prenatal HIV counselling and voluntary testing guidelines in December 1998. We conducted a retrospective chart review of all infants diagnosed with perinatally acquired HIV infection over a 24-month period (August 1999 to July 2001), born to women who became pregnant subsequent to the introduction of these guidelines, with the purpose of determining possible reasons for the failure to eliminate perinatal transmission of HIV in Ontario. Data were extracted from the hospital charts of the infants. As part of the initial history, all HIV-infected mothers seen in our clinic were routinely questioned as to whether they received prenatal HIV counselling, whether they agreed to such testing, whether they thought such testing was performed and whether appropriate therapy was initiated and received. For ethical and legal reasons, no attempt was made to question the physicians who cared for the mothers during pregnancy regarding their antenatal care. An infant was considered to be HIV infected if HIV was detected by DNA polymerase chain reaction (PCR) or culture, or both, on 2 separate occasions. In Ontario, about two-thirds of children diagnosed as being HIV infected receive their care in the HIV/AIDS Family Centered Care Clinic at the Hospital for Sick Children, Toronto. 1 Six infants with perinatally (“vertically”) acquired HIV infection were identified (none of the infants had received blood products). For 4 infants, the diagnosis of HIV

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.662
Threshold uncertainty score0.180

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.019
GPT teacher head0.309
Teacher spread0.289 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Quick stats

Citations0
Published2014
Admission routes1
Has abstractyes

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